Evidence map›Paper›PMID 34410726›Full record

ArticleNano letters2021

Selective Magnetic Nanoheating: Combining Iron Oxide Nanoparticles for Multi-Hot-Spot Induction and Sequential Regulation.

Jesus G Ovejero, Ilaria Armenia, David Serantes, Sabino Veintemillas-Verdaguer, Nicoll Zeballos, Fernando López-Gallego, Cordula Grüttner, Jesús M de la Fuente, María Del Puerto Morales, Valeria Grazu

Open access · hybridAbstract read
In one paragraph

Article in Nano letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 59 citations in OpenAlex.

  1. PCB Coil Pairs for Small Magnetic Volumes.Nanomaterials (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jesus G OvejeroInstitute of Materials Science of Madrid (ICMM-CSIC), Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain.ORCID 0000-0003-3774-6589
Ilaria ArmeniaBioNanoSurf Group, Aragon Nanoscience and Materials Institute (INMA-CSIC-UNIZAR), Edificio I+D, Mariano Esquillor Gómez, 50018 Zaragoza, Spain.ORCID 0000-0002-2854-2907
David SerantesApplied Physics Department and Instituto de Investigacións Tecnolóxicas, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-3860-2133
Sabino Veintemillas-VerdaguerInstitute of Materials Science of Madrid (ICMM-CSIC), Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain.ORCID 0000-0002-3015-1470
Nicoll ZeballosHeterogeneous Biocatalysis Laboratory, Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance, Paseo de Miramón 194, 20014 Donostia-San Sebastián, Spain.
Fernando López-GallegoHeterogeneous Biocatalysis Laboratory, Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance, Paseo de Miramón 194, 20014 Donostia-San Sebastián, Spain.ORCID 0000-0003-0031-1880
Cordula GrüttnerMicromod, Partikeltechnologie GmbH, Friedrich-Barnewitz-Straße 4, 18119 Rostock, Germany.
Jesús M de la FuenteBioNanoSurf Group, Aragon Nanoscience and Materials Institute (INMA-CSIC-UNIZAR), Edificio I+D, Mariano Esquillor Gómez, 50018 Zaragoza, Spain.ORCID 0000-0003-1081-8482
María Del Puerto MoralesInstitute of Materials Science of Madrid (ICMM-CSIC), Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain.ORCID 0000-0002-7290-7029
Valeria GrazuBioNanoSurf Group, Aragon Nanoscience and Materials Institute (INMA-CSIC-UNIZAR), Edificio I+D, Mariano Esquillor Gómez, 50018 Zaragoza, Spain.
Instituto de Ciencia de Materiales de Sevilla · ESUniversidad de Zaragoza · ESIkerbasque · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The contactless heating capacity of magnetic nanoparticles (MNPs) has been exploited in fields such as hyperthermia cancer therapy, catalysis, and enzymatic thermal regulation. Herein, we propose an advanced technology to generate multiple local temperatures in a single-pot reactor by exploiting the unique nanoheating features of iron oxide MNPs exposed to alternating magnetic fields (AMFs). The heating power of the MNPs depends on their magnetic features but also on the intensity and frequency conditions of the AMF. Using a mixture of diluted colloids of MNPs we were able to generate a multi-hot-spot reactor in which each population of MNPs can be selectively activated by adjusting the AMF conditions. The maximum temperature reached at the surface of each MNP was registered using independent fluorescent thermometers that mimic the molecular link between enzymes and MNPs. This technology paves the path for the implementation of a selective regulation of multienzymatic reactions.

Indexed as

Hyperthermia, InducedMagnetite NanoparticlesNanoparticlesMagnetic FieldsMagnetic Iron Oxide NanoparticlesMagneticsMagnetite NanoparticlesEnzymesHot spotIron oxideLocal temperatureMagnetic nanoparticlesMolecular thermometersNanothermometryThermal regulation

Identifiers

PMID34410726
PMCPMC8431726
OpenAlexW3195980739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.