Evidence map›Paper›PMID 34410639›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Isolation and Functional Characterization of Fusobacterium nucleatum Bacteriophage.

Mwila Kabwe, Teagan Brown, Heng Ku, Stuart Dashper, Joseph Tucci

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Journal of oral microbiology · 2026
    Article
  2. Review
  3. Characterisation of novelJournal of oral microbiology · 2025
    Article
  4. Article
  5. Review
  6. Effects ofViruses · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Mwila KabweDepartment of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC, Australia.
Teagan BrownQuadram Institute Bioscience, Norfolk, UK.
Heng KuDepartment of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC, Australia.
Stuart DashperMelbourne Dental School, Faculty of Medicine, Dentistry & Health Science, The University of Melbourne, Melbourne, VIC, Australia.
Joseph TucciDepartment of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Science, La Trobe University, Bendigo, VIC, Australia. j.tucci@latrobe.edu.au.
La Trobe University · AUQuadram Institute · GBUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophages are viruses that specifically lyse bacteria. They have demonstrated potential in applications as antibacterial agents in medicine, agriculture, and environmental remediation. Due to the complex and dynamic nature of the oral microbiome, antibiotic treatment of chronic, polymicrobial oral diseases may lead to dysbiosis. In these diseases, bacteriophages may provide targeted activity against oral bacteria without such disruption to the broader microbial community. In this chapter, we describe the methods for screening samples that may contain bacteriophages against oral pathogenic bacteria, and using the example of FNU1, the bacteriophage we isolated against Fusobacterium nucleatum, describe the process of bacteriophage purification and characterization.

Indexed as

BacteriophagesAnti-Bacterial AgentsBacteriaFusobacterium nucleatumMicrobiotaAnti-Bacterial AgentsBacteriophageEnrichmentFusobacterium nucleatumHost rangeOne-step growth curvePurificationSample screening

Identifiers

PMID34410639
OpenAlexW3194391571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.