Evidence map›Paper›PMID 34410587›Full record

ArticleInternational urology and nephrology2022

Acute kidney injury in hospitalized COVID-19 patients.

Mehmet Kanbay, Alpay Medetalibeyoglu, Asiye Kanbay, Enes Cevik, Cem Tanriover, Arzu Baygul, Naci Şenkal, Hilal Konyaoglu, Timur S Akpinar, Murat Kose and 2 more

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Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mehmet KanbayDepartment of Medicine, Division of Nephrology, Koc University School of Medicine, 34010, Istanbul, Turkey. mkanbay@ku.edu.tr.ORCID http://orcid.org/0000-0002-1297-0675
Alpay MedetalibeyogluDepartment of Medicine, Istanbul University School of Medicine, Istanbul, Turkey.
Asiye KanbayDepartment of Pulmonary Medicine, Atasehir Medicana Hospital, Istanbul, Turkey.
Enes CevikDepartment of Medicine, Koc University School of Medicine, Istanbul, Turkey.
Cem TanrioverDepartment of Medicine, Koc University School of Medicine, Istanbul, Turkey.
Arzu BaygulDepartment of Bioistastics, Koc University School of Medicine, Istanbul, Turkey.
Naci ŞenkalDepartment of Medicine, Istanbul University School of Medicine, Istanbul, Turkey.
Hilal KonyaogluDepartment of Medicine, Istanbul University School of Medicine, Istanbul, Turkey.
Timur S AkpinarDepartment of Medicine, Istanbul University School of Medicine, Istanbul, Turkey.
Murat KoseDepartment of Medicine, Istanbul University School of Medicine, Istanbul, Turkey.
Adrian CovicDepartment of Nephrology, Grigore T. Popa' University of Medicine, Iasi, Romania.
Tufan TukekDepartment of Medicine, Istanbul University School of Medicine, Istanbul, Turkey.
Istanbul University · TRKoç University · TRGrigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) in COVID-19 patients is associated with poor prognosis. However, the incidence, risk factors and potential outcomes of AKI in hospitalized patients are not well studied. MATERIALS AND

methodsThis is a retrospective cohort study conducted in two major university hospitals. Electronic health records of the patients, 18 years or older, hospitalized between 13 April and 1 June 2020 with confirmed COVID-19 were reviewed. We described the incidence and the risk factors for AKI development in COVID-19 patients. Furthermore, we investigated the effects of AKI on the length of hospital and intensive care unit (ICU) stay, the admission rates to ICU, the percentage of patients with cytokine storm and in-hospital mortality rate.

resultsAmong 770 hospitalized patients included in this study, 92 (11.9%) patients developed AKI. The length of hospitalized days (16 vs 9.9, p < 0.001) and days spent in the hospital until ICU admission (3.5 vs. 2.5, p = 0.003) were higher in the AKI group compared to patients without AKI. In addition, ICU admission rates were also significantly higher in patients with AKI (63% vs. 20.7%, p < 0.001). The percentage of patients with AKI who developed cytokine storm was significantly higher than patients without AKI (25.9% vs. 14%, p = 0.009). Furthermore, the in-hospital mortality rate was significantly higher in patients with AKI (47.2% vs. 4.7%, p < 0.001).

conclusionsAKI is common in hospitalized COVID-19 patients. Furthermore, we show that AKI increases the admission rates to ICU and in-hospital mortality. Our findings suggest that AKI should be effectively managed to prevent the adverse outcomes in COVID-19 patients.

Indexed as

Acute Kidney InjuryCOVID-19Cytokine Release SyndromeHospital MortalityHumansIntensive Care UnitsRetrospective StudiesRisk FactorsAcute kidney injuryCOVID-19Hospital stayMortality

Identifiers

PMID34410587
PMCPMC8374419
OpenAlexW3194052636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.