Evidence map›Paper›PMID 34410567›Full record

ReviewMycopathologia2021

A Case of Topical Ofloxacin-Induced Otomycosis and Literature Review.

Mohamed Mahdi Alshahni, Rima Zakzuk Alshahni, Ryuichi Fujisaki, Takashi Tamura, Yuya Shimizu, Chiaki Yamanishi, Koichi Makimura

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Correlation between MIC of econazole nitrate and clinical response in otomycosis.Frontiers in cellular and infection microbiology · 2026
    Article
  2. Prevalence ofOpen veterinary journal · 2025
    Article
  3. Article
  4. [Analysis of fungal infections of external auditory canal and its risk factors in patients with chronic otitis media].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mohamed Mahdi AlshahniLaboratory of Medical Mycology and Space Environmental Medicine, School of Medicine, Graduate School of Medicine, Teikyo University, 2-11-1 Kaga, Itabashi, Tokyo, 173-8605, Japan.
Rima Zakzuk AlshahniTeikyo University Institute of Medical Mycology, Tokyo, Japan.
Ryuichi FujisakiDepartment of Sports and Medical Science, Faculty of Medical Technology, Teikyo University, Itabashi, Tokyo, Japan.
Takashi TamuraTeikyo University Institute of Medical Mycology, Tokyo, Japan.
Yuya ShimizuDepartment of Otolaryngology, Teikyo University Hospital, Itabashi, Tokyo, Japan.
Chiaki YamanishiTeikyo University Institute of Medical Mycology, Tokyo, Japan.
Koichi MakimuraLaboratory of Medical Mycology and Space Environmental Medicine, School of Medicine, Graduate School of Medicine, Teikyo University, 2-11-1 Kaga, Itabashi, Tokyo, 173-8605, Japan. makimura@med.teikyo-u.ac.jp.ORCID http://orcid.org/0000-0003-1645-3445
Teikyo University · JPTeikyo University Hospital · JPTeikyo University of Science · JP

Funding

Japan Agency for Medical Research and Development JP20fk108094
6 · The paper itself

Abstract

The prevalence of fungal otitis externa, or otomycosis, has been increasing in recent decades. Fungi may act as primary pathogens in this condition, or they may occur as secondary infections after prolonged ototopical treatment with antibiotics, which alters the flora of the external auditory canal (EAC) and enables overgrowth of its fungal inhabitants. We report here a case of otomycosis by Candida parapsilosis, Malassezia obtusa, and Malassezia furfur as a secondary infection following prolonged otic ofloxacin treatment. To the best of our knowledge, although isolation of C. parapsilosis and M. furfur from the EAC is not uncommon, the recovery of M. obtusa has not yet been reported. We also conducted a literature review of the searchable data on PubMed concerning the isolation of Malassezia species from the human EAC.

Indexed as

MalasseziaOtitis ExternaOtomycosisFungiHumansOfloxacinOfloxacinCandidaMalasseziaOfloxacinOtitis externaOtomycosis

Identifiers

PMID34410567
OpenAlexW3195613114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.