Evidence map›Paper›PMID 34410503›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021

Brace treatment for scoliosis secondary to chiari malformation type 1 or syringomyelia without neurosurgical intervention: A matched comparison with idiopathic scoliosis.

Tianyuan Zhang, Hongda Bao, Xin Zhang, Shibin Shu, Zhen Liu, Xu Sun, Yong Qiu, Zezhang Zhu

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tianyuan ZhangSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Hongda BaoSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Xin ZhangSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Shibin ShuSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Zhen LiuSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Xu SunSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Yong QiuSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Zezhang ZhuSpine Surgery, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China. zhuzezhang@126.com.ORCID 0000-0002-6411-4619
Nanjing Drum Tower Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effectiveness of brace treatment in patients with Chiari malformation type 1 (CM-1) or syringomyelia associated scoliosis without neurosurgical intervention.

methodsThis was a retrospective case-control study. 34 CM-1 or syringomyelia (CMS) patients who received brace treatment without neurosurgical intervention were recruited. Another 68 matched patients with idiopathic scoliosis who received bracing served as the control group. The matching criteria included gender, age (± 1 years), Risser sign (± 1 grade), initial curve magnitude (± 5°), curve patterns and follow-up time (± 6 months). Patients who encountered curve progression and scoliosis surgery were compared between different groups.

resultsUntil the last visit, 16 (47%) patients in CMS group and 18 (26%) patients in IS group occurred curve progression; 9 (26%) patients and 15 (22%) patients underwent scoliosis surgery, respectively. Compared to idiopathic scoliosis, patients with CMS-associated scoliosis had a significantly higher rate of curve progression (P = 0.038). However, no significant difference was observed between two groups regarding to the rate of surgery (P = 0.867). Patients with combined CM-1 and syringomyelia had a higher rate of surgery than patients with isolated CM-1 or syringomyelia (P = 0.049). The double major curve pattern was identified as the risk factor for curve progression.

conclusionBrace treatment is effective for CMS-associated scoliosis without neurosurgical intervention. Compared to idiopathic scoliosis, brace can provide similar prevention for scoliosis surgery in CMS patients, but slight or moderate curve progression may occur. Specifically, patients with combined CM-1 and syringomyelia should be followed closely with a higher expectation of curve progression.

Indexed as

Arnold-Chiari MalformationScoliosisSyringomyeliaBracesCase-Control StudiesDisease ProgressionHumansRetrospective StudiesTreatment OutcomeBrace treatmentChiari malformationCurve progressionScoliosisSyringomyelia

Identifiers

PMID34410503
OpenAlexW3195973548

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.