Evidence map›Paper›PMID 34410498›Full record

Trial reportClinical oral investigations2022

Is the at-home bleaching treatment applied only on the lingual surface as effective as that on the buccal surface? A randomized clinical trial.

Luciana Mendonça Silva, Ítalo Augusto da Costa Lacerda, Daniela Bandeira Dos Santos, Fernando José Herkrath, Karine Letícia da Silva, Alessandro Dourado Loguercio, Leandro de Moura Martins

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Evaluating the Efficiency and Tooth Sensitivity of a Novel Whitening Strip: A Randomized, Double-Blind Controlled Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luciana Mendonça SilvaSchool of Dentistry, Graduate Program in Dentistry, Federal University of Amazonas, Manaus, AM, Brazil.
Ítalo Augusto da Costa LacerdaSchool of Dentistry, Graduate Program in Dentistry, Federal University of Amazonas, Manaus, AM, Brazil.
Daniela Bandeira Dos SantosSchool of Dentistry, Federal University of Amazonas, Manaus, AM, Brazil.
Fernando José HerkrathInstituto Leônidas E Maria Deane, Fundação Oswaldo Cruz, State University of Amazonas, Manaus, AM, Brazil.
Karine Letícia da SilvaDepartament of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, PR, Brazil.
Alessandro Dourado LoguercioDepartament of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, PR, Brazil. aloguercio@hotmail.com.
Leandro de Moura MartinsSchool of Dentistry, Graduate Program in Dentistry, Federal University of Amazonas, Manaus, AM, Brazil.
Universidade Federal do Amazonas · BRUniversidade Estadual de Ponta Grossa · BRFundação Oswaldo Cruz · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 308286/2019-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

objectivesThis double-blind randomized clinical trial compared the effectiveness and bleaching sensitivity (BS) of at-home dental bleaching performed on the buccal surface and on the lingual surface.

methodsUsing a split-mouth design, 25 patients were assigned to two bleaching groups: 10% hydrogen peroxide (White Class 10%, FGM) applied once daily for 60 min to the buccal surface (BSB) and 10% hydrogen peroxide (White Class 10%, FGM) applied once daily for 60 min to the lingual surface (LSB), both for 14 days. The color was evaluated before bleaching, after the first and second weeks, and 1 month after the bleaching using Vita Classical and Vita Bleachedguide scales and a Vita Easyshade spectrophotometer. BS was recorded daily using a 0-4 numerical rating scale and a 0-10 visual analogue scale. The following statistical tests were used: color changes (Mann-Whitney), absolute risk of BS (McNemar's exact), and the intensity of BS (Mann-Whitney). In all statistical tests, the significance level was 5%.

resultsSignificant bleaching was observed after the end of bleaching in both groups, with higher bleaching effectiveness for BSB when compared to LSB (p < 0.05). Regarding BS, no significant difference was observed between groups (p = 1.00).

conclusionsThe 10% hydrogen peroxide (White Class 10%, FGM) applied in at-home bleaching performed on the lingual surface did not promote a similar result of color change compared to on the buccal surface. Regarding BS, there was no significant difference between the groups. CLINICAL RELEVANCE: The at-home bleaching performed on the lingual surface promotes a lower result in the color change. BS is similar between the groups. CLINICAL TRIAL REGISTRATION NUMBER: RBR-283byt.

Indexed as

Dentin SensitivityTooth BleachingTooth Bleaching AgentsHumansHydrogen PeroxideTreatment OutcomeHydrogen PeroxideTooth Bleaching AgentsDentin sensitivityHydrogen peroxideRandomized clinical trialTooth bleaching

Identifiers

PMID34410498
OpenAlexW3196140316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.