ArticleGenome biology and evolution2021
Demographic History of the Brown Bear (Ursus arctos) on Hokkaido Island, Japan, Based on Whole-Genomic Sequence Analysis.
Article in Genome biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Whole-Genome Sequencing Revealed Local Genetic Differences and Multi-Layered Genetic Structure in Asian Brown Bear (Ursus arctos) Populations.Genome biology and evolution · 2026Article
- Male-Biased Dispersal Leads to Expansion After Decline: The Hokkaido Brown Bear (Ecology and evolution · 2026Article
- Linking Measures of Inbreeding and Genetic Load to Demographic Histories Across Three Species of Bears.Evolutionary applications · 2025Article
- Late Pleistocene polar bear genomes reveal the timing of allele fixation in key genes associated with Arctic adaptation.BMC genomics · 2024Article
- Evidence of population genetic structure in Ecuadorian Andean bears.Scientific reports · 2024Article
- The origins and diversification of Holarctic brown bear populations inferred from genomes of past and present populations.Proceedings. Biological sciences · 2024Article
- Genetic architecture and evolution of color variation in American black bears.Current biology : CB · 2023Article
- A Beary Good Genome: Haplotype-Resolved, Chromosome-Level Assembly of the Brown Bear (Ursus arctos).Genome biology and evolution · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies of the brown bear (Ursus arctos) on Hokkaido Island, Japan, have detected three geographically distinct subpopulations representing different mitochondrial lineages and shown that gene flow between subpopulations has occurred due to male-biased dispersal. In this study, we determined whole-genomic sequences for six Hokkaido brown bears and analyzed these data along with previously published genomic sequences of 17 brown bears from other parts of the world. We found that the Hokkaido population is genetically distinct from the other populations, keeping genetic diversity higher than the endangered populations in western Europe but lower than most populations on the continents. A reconstruction of historical demography showed no increase in population size for the Hokkaido population during the Eemian interglacial period (130,000-114,000 years ago). In a phylogenetic analysis of the autosomal data, the Hokkaido population formed a clade distinct from North American and European populations, showing that it has maintained genetic diversity independently from continental populations following geographical isolation on the island. This autosomal genetic similarity contrasts with the geographically separate mitochondrial lineages on Hokkaido and indicates the occurrence of male-driven gene flow between subpopulations.
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