Evidence map›Paper›PMID 34410360›Full record

ArticleBriefings in bioinformatics2021

Application of artificial intelligence and machine learning for COVID-19 drug discovery and vaccine design.

Hao Lv, Lei Shi, Joshua William Berkenpas, Fu-Ying Dao, Hasan Zulfiqar, Hui Ding, Yang Zhang, Liming Yang, Renzhi Cao

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao LvCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
Lei ShiDepartment of Spine Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200433, China.
Joshua William BerkenpasDepartment of Computer Science, Pacific Lutheran University, Tacoma 98447, USA.
Fu-Ying DaoCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
Hasan ZulfiqarCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
Hui DingCenter for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
Yang ZhangInnovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Liming YangDepartment of Pathophysiology, Harbin Medical University-Daqing, Daqing, 163319, China.
Renzhi CaoDepartment of Computer Science, Pacific Lutheran University, Tacoma 98447, USA.ORCID 0000-0002-8345-343X

Funding

Natural Sciences Undergraduate Research Program at Pacific Lutheran University
6 · The paper itself

Abstract

The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has led to a dramatic loss of human life worldwide. Despite many efforts, the development of effective drugs and vaccines for this novel virus will take considerable time. Artificial intelligence (AI) and machine learning (ML) offer promising solutions that could accelerate the discovery and optimization of new antivirals. Motivated by this, in this paper, we present an extensive survey on the application of AI and ML for combating COVID-19 based on the rapidly emerging literature. Particularly, we point out the challenges and future directions associated with state-of-the-art solutions to effectively control the COVID-19 pandemic. We hope that this review provides researchers with new insights into the ways AI and ML fight and have fought the COVID-19 outbreak.

Indexed as

COVID-19 Drug TreatmentDrug DiscoveryArtificial IntelligenceCOVID-19COVID-19 VaccinesDrug DesignHumansMachine LearningPandemicsSARS-CoV-2COVID-19 Vaccinesartificial intelligenceCOVID-19drugmachine learningSARS-CoV-2vaccine

Identifiers

PMID34410360
PMCPMC8511807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.