ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2021
Variation in incidence, prevention and treatment of persistent air leak after lung cancer surgery.
Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Prediction models for prolonged air leak after pulmonary surgery: a systematic review and critical appraisal.Frontiers in oncology · 2026Pooled it
- Recommendations for the standardization and management of prolonged air leaks in lung surgery.European journal of medical research · 2025Pooled it
- Construction and validation of a nomogram for predicting prolonged air leak after minimally invasive pulmonary resection.World journal of surgical oncology · 2022Trial
- Pleura organoid transplantation facilitates visceral pleural repair through CD133Experimental & molecular medicine · 2026Article
- Intraoperative Volume Decay Measured Through Mechanical Ventilation as a Predictor of Prolonged Postoperative Air Leak After Uniportal Video-Assisted Thoracic Surgery Lung Resection.Journal of personalized medicine · 2026Article
- Endoluminal approaches to postoperative air leaks.Journal of thoracic disease · 2026Review
- NODRAIN study protocol: a non-interventional, prospective study for evaluating the effectiveness of intraoperative ventilation for the prediction of postoperative air leak in major pulmonary resections by conventional or robotic thoracoscopy.Journal of thoracic disease · 2026Article
- Utilization of Lung Cancer Registries in Learning Health Systems for Health Care Improvement.JCO clinical cancer informatics · 2025Review
- Risk factors and clinical impact of prolonged air leak following video-assisted thoracoscopic surgery: a retrospective cohort study.Frontiers in medicine · 2025Article
- Efficacy of fibrin sealant for bedside pleurodesis in patients with prolonged air leak after lung cancer surgery: a comparative study.Frontiers in surgery · 2025Article
- Respiratory endoscopy intervention in 12 patients with refractory persistent air leakage after pulmonary surgery: a preliminary study of case series.Journal of cardiothoracic surgery · 2024Article
- Incidence of air leaks in patients undergoing robotic thoracic surgery and video-assisted thoracic surgery.Nagoya journal of medical science · 2024Article
- Suitable Patient Selection and Optimal Timing of Treatment for Persistent Air Leak after Lung Resection.Journal of clinical medicine · 2024Article
- The safety and efficacy of additional chest tube placement in patients with prolonged air leaks after pulmonary resection: a propensity score-matched analysis.Frontiers in medicine · 2024Article
- Sealing effectiveness of a novel NHS-POx based patch: experiments in a dynamicJournal of thoracic disease · 2023Article
- Prolonged air leak after robotic lung resection: a narrative review.Journal of thoracic disease · 2023Review
- Pulmonary function changes after sublobar resection in patients with peripheral non-subpleural nodules.BMC surgery · 2022Article
- A novel system applying artificial intelligence in the identification of air leak sites.JTCVS techniques · 2022Article
- Treatment of a pneumatocele in a COVID-19 patient with endobronchial valves.BMJ case reports · 2022Article
- Efficacy of multi-groove silicone drains in single-port video-assisted thoracoscopic lung cancer surgery and their effect on C-reactive protein: a single-center experience.Journal of thoracic disease · 2021Article
Corrections and comments
- Commented on by
Authors and funding
10 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPersistent air leak (PAL; >5 days after surgery) is the most common complication after pulmonary resection and associated with prolonged hospital stay and increased morbidity. Literature is contradictory about the prevention and treatment of PAL. Variation is therefore hypothesized. The aim of this study is to understand the variation in the incidence, preventive management and treatment of PAL.
methodsData from the Dutch Lung Cancer Audit for Surgery were combined with results of an online survey among Dutch thoracic surgeons. The national incidence of PAL and case-mix corrected between-hospital variation were calculated in patients who underwent an oncological (bi)lobectomy or segmentectomy between January 2012 and December 2018. By multivariable logistic regression, factors associated with PAL were assessed. A survey was designed to assess variation in (preventive) management and analysed using descriptive statistics. Hospital-level associations between management strategies and PAL were assessed by univariable linear regression.
resultsOf 12 382 included patients, 9.0% had PAL, with a between-hospital range of 2.6-19.3%. Factors associated with PAL were male sex, poor lung function, low body mass index, high American Society of Anesthesiologists (ASA) score, pulmonary comorbidity, upper lobe resection, (bi)lobectomy (vs segmentectomy), right-sided tumour and robotic-assisted thoracic surgery. Perioperative (preventive) management of PAL differed widely between hospitals. When using water seal compared to suction drainage, the average incidence of PAL decreased 2.9%.
conclusionsIn the Netherlands, incidence and perioperative (preventive) management of PAL vary widely. Using water seal instead of suction drainage and increasing awareness are potential measures to reduce this variation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.