Evidence map›Paper›PMID 34409967›Full record

ArticleThe journal of nutrition, health & aging2021

Nutritional Status and Adverse Outcomes in Older Depressed Inpatients: A Prospective Study.

Z M Lobato, A C Almeida da Silva, S M Lima Ribeiro, M M Biella, A Santos Silva Siqueira, T Correa de Toledo Ferraz Alves, R Machado-Vieira, M K Borges, R C Oude Voshaar, I Aprahamian

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07204444 (Equipping the Aging Network to Address Social Isolation, Loneliness, and Elevated Suicide Risk Among Vulnerable Older Adults), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07204444 nacompletednot on this map

Equipping the Aging Network to Address Social Isolation, Loneliness, and Elevated Suicide Risk Among Vulnerable Older Adults: A Partially Nested Randomized Controlled Trial of the BE WITH Innovation

TypeinterventionalSponsorUniversity of FloridaRan2021 to 2024Enrolled671ConditionsOlder Adults, Mental Health, Depression, LonelinessArmsstandardized and manualized warm calls from providers trained in the BE training, standardized and manualized warm calls from providers trained in the BE training + ASIST training
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Z M LobatoIvan Aprahamian, MD, MS, PhD, FACP. Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil. R. Dr. Ovídio Pires de Campos, 785, 1º andar, sala 1C 015. ZIP: 05403-903. Phone: (11) 2661-6963. São Paulo, Brazil, E-mail: ivan.aprahamian@gmail.com.
A C Almeida da Silva
S M Lima Ribeiro
M M Biella
A Santos Silva Siqueira
T Correa de Toledo Ferraz Alves
R Machado-Vieira
M K Borges
R C Oude Voshaar
I Aprahamian
Universidade de São Paulo · BRUniversity of Groningen · NLThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSignificant weight loss and/or loss of appetite is a criterion of a depressive episode. While malnutrition is associated with many adverse health outcomes, the impact of malnutrition in late-life depression has hardly been examined. The present study aims to (1) evaluate the prevalence of malnutrition in depressed older inpatients, and (2) whether and which indices of malnutrition predict adverse health outcomes in late-life depression.

designA prospective study at 6 months follow-up.

settingA University-based psychiatric hospital.

participants105 older adults (psychiatric inpatients suffering from unipolar MDD). MEASUREMENTS: Participants were evaluated according the Mini Nutritional Assessment (MNA) and anthropometric measures to assess their nutritional status. Multiple regression analyses were used to evaluate the association between the MNA score as well as anthropometric measures with either falls or rehospitalization for any reason.

resultsBased on the MNA score, 78 (74.3%) patients were at risk of malnutrition and 13 (12.4%) actually presented malnutrition. Malnutrition was associated with a higher age, frailty, lower body mass index, and smaller calf circumference. During follow-up, 21 (20%) patients fell, 27 (25.7%) were rehospitalized, and 3 died (2.9%). The MNA score was associated with adverse health outcomes, but a low calf circumference predicted falling (OR 4.93 [95% CI: 1.42-17.2], p=.012) and a higher calf circumference rehospitalization (OR 1.17 [95% CI: 1.01-1.35], p=.032).

conclusionMalnutrition is prevalent in older depressed inpatients. In contrast to subjective proxies for malnutrition, which are common in depression, only objective measures of malnutrition predict adverse health outcomes such as falls and rehospitalization.

Indexed as

Geriatric AssessmentMajor Depressive DisorderMalnutritionNutritional StatusNutrition AssessmentAgedAged, 80 and overAnorexiaFemaleHumansInpatientsMaleMiddle AgedProspective StudiesWeight LossfallshospitalizationMajor depressive disordernutritional statusolder adults

Identifiers

PMID34409967
PMCPMC12280593
OpenAlexW3157400932

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.