Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors at 2 institutions in 1 country.
Sequoyah Reynoso *Department of Pathology, School of Medicine, University of California San Diego, San Diego, United States.
Vanessa Castillo *Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, San Diego, United States.ORCID 0000-0002-4182-8846
Gajanan Dattatray Katkar *Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, San Diego, United States.
Inmaculada Lopez-SanchezDepartment of Medicine, School of Medicine, University of California San Diego, San Diego, United States.
Sahar TaheriDepartment of Computer Science and Engineering, Jacob's School of Engineering, University of California San Diego, San Diego, United States.
Celia EspinozaDepartment of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, San Diego, United States.
Cristina RohenaDepartment of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, San Diego, United States.
Debashis SahooDepartment of Computer Science and Engineering, Jacob's School of Engineering, University of California San Diego, San Diego, United States.
Pascal GagneuxDepartment of Pathology, School of Medicine, University of California San Diego, San Diego, United States.ORCID 0000-0001-9599-9838
Pradipta GhoshDepartment of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, San Diego, United States.ORCID 0000-0002-8917-3201
University of California San Diego · USVeterans Health Administration · US
Funding
UCSD Cancer Center Training Program in Drug DevelopmentT32CA121938 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Michael Bouvet, Dwayne G. Stupack · 2006 to 2026
$10.3M
Training Grant in GastroenterologyT32DK007202 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA · 1985 to 2022
$7.7M
Spatial Regulation of RGS and G Protein SignalingR01CA100768 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA · 2003 to 2019
$7.4M
Modulation of Macrophage Polarization by Heterotrimeric G proteins: Implications of Gastrointestinal InflammationR01AI141630 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pradipta Ghosh · 2019 to 2026
$3.2M
Integrators of Metastatic PotentialR01CA238042 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA, LUKER, GARY D · 2019 to 2023
$2.3M
Summer Student Research on the Application of Boolean AnalysisR01GM138385 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAHOO, DEBASHIS · 2020 to 2023
$2.0M
Modulation of G proteins by Growth FactorsR01CA160911 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA · 2013 to 2017
$1.8M
Glycan Diversity and Anti-Glycan Antibodies as Barriers to Gene FlowR01GM095882 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GAGNEUX, PASCAL · 2011 to 2015
$1.4M
G Protein pathways as Novel Therapeutic and Diagnostic Targets in Liver FibrosisR01DK099226 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA · 2014 to 2016
$698k
Glycan array for phenotype-driven capture and genotyping of viruses in primary isolatesR21AI129894 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GAGNEUX, PASCAL, GODULA, KAMIL · 2016 to 2017
$601k
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
For a sperm to successfully fertilize an egg, it must first undergo capacitation in the female reproductive tract and later undergo acrosomal reaction (AR) upon encountering an egg surrounded by its vestment. How premature AR is avoided despite rapid surges in signaling cascades during capacitation remains unknown. Using a combination of conditional knockout (cKO) mice and cell-penetrating peptides, we show that GIV (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility. · full record | OpenQuestion