Evidence map›Paper›PMID 34409864›Full record

ArticleGlobal spine journal2023

Myelopathic Patients Undergoing Severe Pediatric Spinal Deformity Surgery Can Improve Neurologic Function to That of Non-Myelopathic Patients by 1-Year Postoperative.

Meghan Cerpa, Scott L Zuckerman, Lawrence G Lenke, Michael P Kelly, Burt Yaszay, Peter Newton, Paul Sponseller, Mark Erickson, Sumeet Garg, Joshua Pahys and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Meghan CerpaDepartment of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.ORCID 0000-0002-5931-7067
Scott L ZuckermanDepartment of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Lawrence G LenkeDepartment of Orthopaedics, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Michael P KellyDepartment of Orthopaedics, Washington University, St. Louis, MO, USA.ORCID 0000-0001-6221-7406
Burt YaszayRady Children's Hospital, San Diego, CA, USA.
Peter NewtonRady Children's Hospital, San Diego, CA, USA.
Paul SponsellerJohns Hopkins University, Baltimore, MD, USA.
Mark EricksonChildren's Hospital Colorado Aurora, Aurora, CO, USA.
Sumeet GargChildren's Hospital Colorado Aurora, Aurora, CO, USA.
Joshua PahysShriners Hospitals for Children, Philadelphia, PA, USA.
Amer SamdaniShriners Hospitals for Children, Philadelphia, PA, USA.
Patrick CahillChildren's Hospital of Philadelphia, PA, USA.
Richard McCarthyDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
David BumpassDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Daniel SucatoTexas Scottish Rite Hospital for Children Dallas, TX, USA.
Oheneba Boachie-AdjeiFOCOS Orthopedic Hospital, Accra, Ghana.
Suken ShahNemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA.
Munish GuptaDepartment of Orthopaedics, Washington University, St. Louis, MO, USA.ORCID 0000-0002-4711-4377
Columbia University Irving Medical Center · USChildren's Hospital Colorado · USRady Children's Hospital-San Diego · USShriners Hospitals for Children - Philadelphia · USUniversity of Arkansas for Medical Sciences · USWashington University in St. Louis · USAlfred I. duPont Hospital for Children · USChildren's Hospital of Philadelphia · USJohns Hopkins University · USTexas Scottish Rite Hospital for Children · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designMulti-center, prospective, observational cohort.

objectiveTo compare myelopathic vs. non-myelopathic ambulatory patients in short- and long-term neurologic function, operative treatment, and patient-reported outcomes.

methodsPediatric deformity patients from 16 centers were enrolled with the following inclusion criteria: aged 10-21 years-old, a Cobb angle ≥100° in either the coronal or sagittal plane or any sized deformity with a planned 3-column osteotomy, and community ambulators. Patients were dichotomized into 2 groups: myelopathic (abnormal preoperative neurologic exam with signs/symptoms of myelopathy) and non-myelopathic (no clinical signs/symptoms of myelopathy).

resultsOf 311 patients with an average age of 14.7 ± 2.8 years, 29 (9.3%) were myelopathic and 282 (90.7%) were non-myelopathic. There was no difference in age (

conclusionIn severe spinal deformity pediatric patients presenting with preoperative myelopathy undergoing spinal reconstructive surgery, myelopathic patients can expect significant improvement in neurologic function postoperatively. At 1-year and 2-year postoperative, neurologic function was no different between groups. While non-myelopathic patients had significantly higher postoperative outcomes in SRS mental-health, function, and total-score, both groups had significantly improved outcomes in every SRS domain compared to preoperative.

Indexed as

myelopathyneurologic deficitneurologic functionpediatric spine surgeryscoliosissevere pediatric spinal deformity

Identifiers

PMID34409864
PMCPMC10416607
OpenAlexW3193386264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.