Evidence map›Paper›PMID 34409771›Full record

ReviewPhysiological reports2021

The role of spinal cord extrasynaptic α

Rodolfo Delgado-Lezama, Mariana Bravo-Hernández, Úrzula Franco-Enzástiga, Yarim E De la Luz-Cuellar, Nara S Alvarado-Cervantes, Guadalupe Raya-Tafolla, Luis A Martínez-Zaldivar, Alberto Vargas-Parada, Erick J Rodríguez-Palma, Guadalupe C Vidal-Cantú and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Cys-loop receptors on cannabinoids: All high?Frontiers in physiology · 2022
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Ion channel long non-coding RNAs in neuropathic pain.Pflugers Archiv : European journal of physiology · 2022
    Review
  11. Review
  12. The role of spinal cord extrasynaptic αPhysiological reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Rodolfo Delgado-LezamaDepartamento de Fisiología, Biofísica y Neurociencias, Cinvestav, Mexico City, Mexico.ORCID 0000-0003-3048-3640
Mariana Bravo-HernándezNeuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, CA, USA.
Úrzula Franco-EnzástigaNeurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
Yarim E De la Luz-CuellarNeurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
Nara S Alvarado-CervantesDepartamento de Fisiología, Biofísica y Neurociencias, Cinvestav, Mexico City, Mexico.
Guadalupe Raya-TafollaDepartamento de Fisiología, Biofísica y Neurociencias, Cinvestav, Mexico City, Mexico.
Luis A Martínez-ZaldivarDepartamento de Fisiología, Biofísica y Neurociencias, Cinvestav, Mexico City, Mexico.
Alberto Vargas-ParadaDepartamento de Fisiología, Biofísica y Neurociencias, Cinvestav, Mexico City, Mexico.
Erick J Rodríguez-PalmaNeurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
Guadalupe C Vidal-CantúNeurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
Crystell G Guzmán-PriegoMechanisms of Pain Laboratory, División Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, Mexico.ORCID 0000-0002-8228-1314
Jorge E Torres-LópezMechanisms of Pain Laboratory, División Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, Mexico.ORCID 0000-0001-7677-6313
Janet MurbartiánDepartamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
Ricardo FelixDepartamento de Biología Celular, Cinvestav, Mexico City, Mexico.
Vinicio Granados-SotoNeurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.ORCID 0000-0003-1038-8400
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXHospital Regional de Alta Especialidad del Bajío · MXUniversidad Juárez Autónoma de Tabasco · MXUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain is an incapacitating condition that affects a large population worldwide. Until now, there is no drug treatment to relieve it. The impairment of GABAergic inhibition mediated by GABA

Indexed as

AnalgesicsAnimalsChronic PainGABA-A Receptor AntagonistsHumansNociceptionReceptors, GABA-ASpinal CordAnalgesicsGABA-A Receptor AntagonistsReceptors, GABA-Aextrasynaptic GABAA receptorsGABAA and GABAB receptorsHoffmann reflexPain

Identifiers

PMID34409771
PMCPMC8374381
OpenAlexW3193297087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.