Evidence map›Paper›PMID 34409579›Full record

ArticleCardiovascular engineering and technology2022

A Robot Mimicking Heart Motions: An Ex-Vivo Test Approach for Cardiac Devices.

Adrian Zurbuchen, Aloïs Pfenniger, Sammy Omari, Tobias Reichlin, Rolf Vogel, Andreas Haeberlin

Abstract read
In one paragraph

Article in Cardiovascular engineering and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adrian ZurbuchenDepartment of Cardiology, Bern University Hospital, University of Bern, Freiburgstrassse 3, 3010, Bern, Switzerland. adrian4zurbuchen@gmail.com.ORCID 0000-0003-0920-378X
Aloïs PfennigerARTORG Center for Biomedical Engineering, University of Bern, Bern, Switzerland.
Sammy OmariDepartment of Cardiology, Bern University Hospital, University of Bern, Freiburgstrassse 3, 3010, Bern, Switzerland.
Tobias ReichlinDepartment of Cardiology, Bern University Hospital, University of Bern, Freiburgstrassse 3, 3010, Bern, Switzerland.
Rolf Vogel *Department of Cardiology, Bürgerspital Solothurn, Solothurn, Switzerland.
Andreas Haeberlin *Department of Cardiology, Bern University Hospital, University of Bern, Freiburgstrassse 3, 3010, Bern, Switzerland. andreas.haeberlin@insel.ch.ORCID 0000-0002-9283-0110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe pre-clinical testing of cardiovascular implants gains increasing attention due to the complexity of novel implants and new medical device regulations. It often relies on large animal experiments that are afflicted with ethical and methodical challenges. Thus, a method for simulating physiological heart motions is desired but lacking so far.

methodsWe developed a robotic platform that allows simulating the trajectory of any point of the heart (one at a time) in six degrees of freedom. It uses heart motion trajectories acquired from cardiac magnetic resonance imaging or accelero-meter data. The rotations of the six motors are calculated based on the input trajectory. A closed-loop controller drives the platform and a graphical user interface monitors the functioning and accuracy of the robot using encoder data.

resultsThe robotic platform can mimic physiological heart motions from large animals and humans. It offers a spherical work envelope with a radius of 29 mm, maximum acceleration of 20 m/s

conclusionThe novel robotic approach allows reproducing heart motions with high accuracy and repeatability. This may benefit the device development process and allows re-using previously acquired heart motion data repeatedly, thus avoiding animal trials.

Indexed as

Defibrillators, ImplantableRoboticsAnimalsEx-vivoHexapodInverse kinematicSimulatorStewart platform

Identifiers

PMID34409579
PMCPMC9114091

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.