ArticleInternational journal of colorectal disease2021
Further research on the clinical relevance of the ulcerative colitis colonoscopic index of severity for predicting 5-year relapse.
Article in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 12 citations in OpenAlex.
- A Scoping Review of Endoscopic Assessment Considering Disease Extent in Ulcerative Colitis: Insights for the Artificial Intelligence Era.Gut and liver · 2026Article
- The protective effect of naringenin on ulcerative colitis in mice through increasing Nrf2 pathway activity.Acta biochimica et biophysica Sinica · 2025Article
- Fecal calprotectin and endoscopic scores: The cornerstones in clinical practice for evaluating mucosal healing in inflammatory bowel disease.World journal of gastroenterology · 2024Article
- New insights into the interactions between the gut microbiota and the inflammatory response to ulcerative colitis in a mouse model of dextran sodium sulfate and possible mechanisms of action for treatment with PE&AFWE.Animal models and experimental medicine · 2024Article
- Deep mucosal healing in ulcerative colitis: how deep is better?Frontiers in medicine · 2024Review
- Comparison of fecal calprotectin levels and endoscopic scores for predicting relapse in patients with ulcerative colitis in remission.World journal of gastroenterology · 2023Article
- [Value of Improved Mayo Endoscopic Score for evaluating treatment efficacy for active ulcerative colitis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- Artemisinin Alleviates Intestinal Inflammation and Metabolic Disturbance in Ulcerative Colitis Rats Induced by DSS.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Histologic healing and factors associated with complete remission following conventional treatment in ulcerative colitis.Therapeutic advances in gastroenterology · 2022Article
- The potential mechanism of huazhuojiedu decoction in the treatment of ulcerative colitis based on network pharmacology and experimental validation.Frontiers in pharmacology · 2022Article
- How to assess endoscopic disease activity in ulcerative colitis in 2022.Annals of gastroenterologyReview
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Authors and funding
11 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe ulcerative colitis colonoscopic index of severity (UCCIS) evaluates the state of the entire colonic mucosa in ulcerative colitis. However, no cut-off values of scores for predicting clinical relapse in patients with ulcerative colitis have been established. This study aimed to determine the cut-off values for predicting clinical relapse in patients with ulcerative colitis.
methodsThe endoscopic scores (sum of Mayo endoscopic subscores (S-MES) and UCCIS) of 157 patients with ulcerative colitis experiencing clinical remission and their subsequent clinical course were retrospectively reviewed. The optimal cut-off values for predicting relapse and relapse-free rates were analyzed by receiver operating characteristic analysis.
resultsForty patients with ulcerative colitis experienced relapse within 24 months. The median UCCIS for these patients at the time of study enrollment was significantly higher than that for patients with clinical remission (P < 0.001). The cut-off value of the UCCIS for predicting relapse was 9.8. The relapse-free rate was significantly lower in patients with UCCIS ≥ 9.8 than in those with UCCIS < 9.8 (log-rank test P < 0.001). For patients who experienced relapse within 5 years, the optimal cut-off values for the UCCIS and S-MES were 10.2 and 1, respectively (P = 0.004).
conclusionsThe data from this study indicate that the USSIC is a more relevant score than the S-MES for predicting the time to relapse in patients with ulcerative colitis in remission.
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