ReviewJAAD international2021
Clinical manifestations and treatment outcomes in prurigo pigmentosa (Nagashima disease): A systematic review of the literature.
Review in JAAD international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05469997 (Ketogenic Diet Interventions in Parkinson's Disease), which is not on this map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ketogenic Diet Interventions in Parkinson's Disease: Safeguarding the Gut Microbiome
Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- Clinical and Histopathological Characteristics of Prurigo Pigmentosa: A Case Series.Dermatology practical & conceptual · 2026Article
- Prurigo Pigmentosa Following Bariatric Surgery: A Comprehensive Clinicopathological Review.Dermatology research and practice · 2026Review
- Article
- Prurigo Pigmentosa (Keto Rash) Secondary to an Eating Disorder: A Case Report and Proposed Diagnostic Criteria.Cureus · 2025Article
- Prurigo pigmentosa following laparoscopic sleeve gastrectomy: a case report.Journal of surgical case reports · 2025Article
- Prurigo Pigmentosa Associated with a Ketogenic Diet in a Romanian Patient: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- Prurigo pigmentosa in an African-Canadian patient: Expanding the limited literature on skin of color.SAGE open medical case reports · 2025Article
- Effects of the ketogenic diet on skin-potential benefits and risks.Frontiers in nutrition · 2025Review
- A Rare Case of Prurigo Pigmentosa in Iranian Sibling Couple.Clinical case reports · 2025Article
- [Prurigo pigmentosa: Case report of a German adolescent].Dermatologie (Heidelberg, Germany) · 2024Article
- Dapsone Use in Dermatology.American journal of clinical dermatology · 2024Review
- A case of diabetic ketoacidosis with prurigo pigmentosa as a dermadrome.Diabetology international · 2024Article
- Tetracyclines Revisited: Tetracyclines in the Field of Dermatology.Dermatology (Basel, Switzerland) · 2024Review
- Adult-onset Still's disease: Switch to atypical skin manifestations under anakinra therapy.JAAD case reports · 2023Article
- Dermoscopy and reflection confocal microscope features of pigmented prurigo.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Article
- Prurigo pigmentosa post-bariatric surgery: a case report.AME case reports · 2023Article
- Article
- Prurigo pigmentosa induced by a ketogenic dietEuropean journal of dermatology : EJD · 2022Article
- Article
- Prurigo pigmentosa following a ketogenic diet: a case report.European journal of clinical nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrurigo pigmentosa (PP) is a rare inflammatory dermatosis characterized by pruritic erythematous papules that coalesce to form a reticulate pattern. PP is often misdiagnosed, and patients are treated with ineffective therapies. Although the majority of reports about PP are from East Asia, patients of all backgrounds can be affected.
objectivesTo perform a systematic review of reported PP cases with the purpose of summarizing the clinical presentation and treatment of PP.
methodsMEDLINE and Embase were searched for original articles describing PP. We identified 115 studies from 24 countries representing 369 patients to include in the analysis.
resultsOf the 369 patients included in the analysis, the mean age was 25.6 years (range: 13-72 years) with 72.1% (266 of 369) female. Risk factors or aggravating factors were described in 52.3% (193 of 369) of patients and included dietary changes (25.5%, 94 of 369), friction (8.4%, 31 of 369), sweat (7.6%, 28 of 369), and ketonuria (5.1%, 19 of 369). Of those patients who experienced PP following dietary changes, 40.4% (38 of 94) started a ketogenic diet. Minocycline monotherapy was the most frequently prescribed treatment for PP (20.9%, 77 of 369), achieving complete resolution in 48.1% (37 of 77) of patients.
conclusionsPP is sometimes associated with ketogenic diets and can be effectively managed with oral tetracyclines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.