Evidence map›Paper›PMID 34409358›Full record

ArticleJAAD international2021

The global burden of skin cancer: A longitudinal analysis from the Global Burden of Disease Study, 1990-2017.

Katelyn Urban, Sino Mehrmal, Prabhdeep Uppal, Rachel L Giesey, Gregory R Delost

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAAD international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 6 pooled it
30.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 6 syntheses or guidelines pooled it, 309 citations in OpenAlex.

  1. An evaluation of skin and eye diseases associated with exposure to solar ultraviolet radiation in Central Asia.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
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  8. Phase II (Alliance A091802) Randomized Trial of Avelumab Plus Cetuximab Versus Avelumab Alone in Advanced Cutaneous Squamous Cell Carcinoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
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  11. Application of the Protection Motivation Theory (PMT) in Teaching Skin Cancer Prevention Behaviors in Male Students.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023
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  15. Expert opinion : Radiotherapy in cutaneous squamous cell carcinoma: Recommendations from the DEGRO dermatooncology working group.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Katelyn UrbanLake Erie College of Osteopathic Medicine, Greensburg, Pennsylvania.
Sino MehrmalDepartment of Internal Medicine, Alameda Health System-Highland Hospital, Oakland, California.
Prabhdeep UppalDepartments of Emergency Medicine and Family Medicine, Christiana Care Health System, Newark, Delaware.
Rachel L GieseyDepartment of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Gregory R DelostLake Erie College of Osteopathic Medicine, Greensburg, Pennsylvania.
Lake Erie College of Osteopathic Medicine · USChristiana Care Health System · USHighland Hospital · USUniversity Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite efforts toward the earlier detection and prevention of skin cancer, the prevalence of skin cancers continues to increase. Identifying trends in skin cancer burdens among populations can lead to impactful and sustainable interventions.

methodsWe assessed the global trends in skin cancer from 1990 to 2017 in 195 countries worldwide through the Global Burden of Disease Study (GBD) 2017 database.

resultsThe rate of change in skin cancers between 1990 to 2017 varied among countries. Squamous cell carcinomas increased by 310% during this time, the highest among any neoplasm tracked by the GBD. Men experienced greater age-specific prevalence rates of keratinocyte carcinoma across all ages (

conclusionThe incidence, prevalence, and DALYs of skin cancers are increasing disproportionately among different demographic groups. As a worldwide epidemiological assessment, the GBD 2017 provides frequently updated measures of the skin cancer burden, which may help to direct resources and allocate funding to close the gap in global skin cancer disparities.

Indexed as

basal cell carcinomaBCC, basal cell carcinomasDALYs, disability-adjusted life yearsdisability-adjusted life years (DALYs)Global Burden of Disease Study (GBD) databaseKC, keratinocyte carcinomamelanomaSCC, squamous cell carcinomasSDI, sociodemographic indexsociodemographic index (SDI)squamous cell carcinomaUVR, ultraviolet radiation

Identifiers

PMID34409358
PMCPMC8362234
OpenAlexW3120505984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.