Evidence map›Paper›PMID 34409347›Full record

ArticleJAAD international2021

The global, regional, and national burden of atopic dermatitis in 195 countries and territories: An ecological study from the Global Burden of Disease Study 2017.

Katelyn Urban, Sherman Chu, Rachel L Giesey, Sino Mehrmal, Prabhdeep Uppal, Natalie Nedley, Gregory R Delost

Abstract read
In one paragraph

Article in JAAD international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Review
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  6. Article
  7. Evaluation of Childhood Atopic Dermatitis and Environmental Factors in Turkey with Decision Tree Model.International journal of environmental research and public health · 2025
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  8. Article
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  11. Changes in Childhood Atopic Dermatitis Incidence and Risk Factors Over Time: Results From Two German Birth Cohorts.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
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  12. Article
  13. Effect of herbal medicineFrontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katelyn UrbanLake Erie College of Osteopathic Medicine, Greensburg, Pennsylvania.
Sherman ChuWestern University of Health Sciences, College of Osteopathic Medicine of the Pacific, Northwest, Lebanon, Oregon.
Rachel L GieseyDepartment of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Sino MehrmalDepartment of Internal Medicine, Alameda Health System - Highland Hospital, Oakland, California.
Prabhdeep UppalDepartment of Emergency Medicine and Department of Family Medicine, Christiana Care Health System, Newark, Delaware.
Natalie NedleyLake Erie College of Osteopathic Medicine, Erie, Pennsylvania.
Gregory R DelostLake Erie College of Osteopathic Medicine, Erie, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNumerous population-based studies have focused on the global prevalence of atopic dermatitis (AD), but there are few studies on the global trends of the burden associated with AD.

methodsWe analyzed the global AD trends in 2017 in 195 countries worldwide using the Global Burden of Disease (GBD) Study database, including prevalence rates, age and sex patterns, and AD burden, using disability-adjusted life years (DALYs). Age-standardized DALYs were also compared to the sociodemographic index values of all the countries in 2017.

resultsThe age-specific DALYs in 2017 showed a right-skewed distribution, with the highest DALYs between 1 and 5 years of age. Females had a higher burden of AD throughout all age groups and geographic regions. The GBD super region with the greatest burden of DALYs caused by AD was high income (178.63 DALYs per 100,000 males, 231.8 for females), and the country with the highest DALYs was Sweden (326.91). The GBD super region with the lowest age-standardized DALY burden caused by AD was south Asia (84.51 DALYs per 100,000 males, 100.54 for females).

conclusionThere is a large GBD caused by AD. The observed burden is the greatest in resource-rich countries, females, and young children.

Indexed as

AD, atopic dermatitisage-standardized prevalence ratesatopic dermatitisburdenDALY, disability-adjusted life yeardisability-adjusted life years (DALYs)GBD, global burden of diseaseGlobal Burden of Disease Study (GBD) databaseglobal medicinehealth care disparitiesSDI, sociodemographic indexsociodemographic index (SDI)

Identifiers

PMID34409347
PMCPMC8362298

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.