Evidence map›Paper›PMID 34409259›Full record

ArticleTherapeutic advances in ophthalmology

Effect of pattern scanning laser on macular thickness in diabetic retinopathy.

Nadine Hamed, Logan Vander Woude, Ramak Roohipourmoallai, Collin Ohning, Kathleen A Regan, Siva S R Iyer

Open access · diamondAbstract read
In one paragraph

Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nadine HamedDepartment of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL, USA.
Logan Vander WoudeDepartment of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL, USA.
Ramak RoohipourmoallaiDepartment of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL, USA.
Collin OhningDepartment of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0002-6081-7202
Kathleen A ReganDepartment of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0003-0504-3053
Siva S R IyerAssociate Professor, Department of Ophthalmology, College of Medicine , University of Florida, 1600, SW Archer Road, Gainesville FL, 32610, USA.ORCID https://orcid.org/0000-0002-3442-2311
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigates the effect of pattern scanning laser (PASCAL) panretinal photocoagulation (PRP) on central macular thickness (CMT) and visual acuity (VA) in patients with proliferative diabetic retinopathy (PDR).

methodsThis retrospective non-randomized comparative case series included 262 eyes (163 with macular edema) of 177 patients with PDR. Treatment was PRP alone (137), PRP + anti-vascular endothelial growth factor (VEGF) (69), PRP + focal laser (28), or all three (89). CMT and central macular volume 3 and 6 mm from fovea were analyzed before and 1, 3, and 6 months after PRP. Spot number was plotted against CMT, and linear regression analysis was performed.

resultsFor each treatment group and time point, there was a non-significant relationship between spot number and CMT. In eyes receiving all three treatment modalities, a significant negative relationship was found between spot number and 3-mm volume at 6 months (

conclusionPASCAL PRP ± focal laser or anti-VEGF was not associated with increased development of macular edema or change in VA. PASCAL PRP with focal laser and anti-VEGF may result in a decrease in macular edema.

Indexed as

central macular thicknessdiabetic macular edemamacular volumepan retinal photocoagulationpattern scan laser

Identifiers

PMID34409259
PMCPMC8366200
OpenAlexW3195357820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.