Evidence map›Paper›PMID 34409223›Full record

ArticleJournal of current ophthalmology

Autologous Activated Omental versus Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells in Corneal Alkaline Injury: An Experimental Study.

Athar Shadmani, Mahboobeh Razmkhah, Mohammad Hassan Jalalpoor, Sina Yazdanpanah Lari, Masoomeh Eghtedari

Open access · diamondAbstract read
In one paragraph

Article in Journal of current ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Athar ShadmaniPoostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahboobeh RazmkhahShiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Hassan JalalpoorPoostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sina Yazdanpanah LariDepartment of Computer Science and Engineering, Shiraz University, Shiraz, Iran.
Masoomeh EghtedariPoostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRShiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the effects of two types of mesenchymal stem cells (MSCs), activated omental cells (AOCs), and adipose tissue-derived stem cells (ADSCs) in the healing process of animal model of ocular surface alkali injury.

methodsAn alkaline burn was induced on the ocular surfaces of eighteen rats divided randomly into three groups. The first and second groups received subconjunctival AOCs and ADSCs, respectively. The control group received normal saline subconjunctival injection. On the 90

resultsCorneal neovascularization scores revealed higher neovascularization in the control (0.49 ± 0.12) than the AOC (0.80 ± 0.20,

conclusionsOur results suggest that MSCs, even with different sources, can be used to promote wound healing after corneal chemical burns. However, the ease of harvesting ADSC from more superficial fat sources makes this method more clinically applicable.

Indexed as

Activated omental cellAdipose tissue-derived stem cellCorneal alkaline burnCorneal neovascularizationLimbal stem cell deficiencyMesenchymal stem cellOcular cell therapyOmentum

Identifiers

PMID34409223
PMCPMC8365576
OpenAlexW3184759197

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.