Evidence map›Paper›PMID 34408847›Full record

ArticleHepatic oncology2021

Locoregional therapy patterns and healthcare economic burden of patients with hepatocellular carcinoma in the USA.

Abdalla Aly, Melissa Lingohr-Smith, Jay Lin, Brian Seal

Abstract read
In one paragraph

Article in Hepatic oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdalla AlyAstraZeneca Pharmaceuticals LP, US Medical Affairs: Evidence Generation, Gaithersburg, MD 20878, USA.ORCID https://orcid.org/0000-0001-7411-894X
Melissa Lingohr-SmithNovosys Health, Green Brook, NJ 08812, USA.ORCID https://orcid.org/0000-0002-3046-9278
Jay LinNovosys Health, Green Brook, NJ 08812, USA.ORCID https://orcid.org/0000-0002-6376-8469
Brian SealAstraZeneca Pharmaceuticals LP, US Medical Affairs: Evidence Generation, Gaithersburg, MD 20878, USA.ORCID https://orcid.org/0000-0002-4914-6161

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the locoregional therapy (LRT) patterns and the healthcare economic burden of patients with hepatocellular carcinoma (HCC) in the USA. PATIENTS &

methodsPatients with newly diagnosed HCC were identified from the MarketScan

resultsAmong 2101 patients with HCC, most received embolization therapy as their first LRT treatment (57.8%, n = 1215); 17.1% (n = 360) received ablative therapy and 8.7% (n = 182) radiation therapy; 16.4% (n = 344) received multiple LRTs. After patients received their first LRT treatment, total all-cause healthcare costs averaged $20,316 per patient per month; 70.7% ($14,359) were HCC related.

conclusionAmong newly diagnosed HCC patients treated with LRT in the USA, the economic burden is high.

Indexed as

healthcare economic burdenhepatocellular carcinomalocoregional therapiestreatment patterns

Identifiers

PMID34408847
PMCPMC8369525

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.