Evidence map›Paper›PMID 34408774›Full record

ReviewFrontiers in genetics2021

Myogenic Cell Transplantation in Genetic and Acquired Diseases of Skeletal Muscle.

Olivier Boyer, Gillian Butler-Browne, Hector Chinoy, Giulio Cossu, Francesco Galli, James B Lilleker, Alessandro Magli, Vincent Mouly, Rita C R Perlingeiro, Stefano C Previtali and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 15 institutions in 7 countries.

Olivier BoyerDepartment of Immunology & Biotherapy, Rouen University Hospital, Normandy University, Inserm U1234, Rouen, France.
Gillian Butler-BrowneSorbonne Université, Inserm, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
Hector ChinoyManchester Centre for Clinical Neurosciences, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, United Kingdom.
Giulio CossuDivision of Cell Matrix Biology & Regenerative Medicine, The University of Manchester, Manchester, United Kingdom.
Francesco GalliNational Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, United Kingdom.
James B LillekerManchester Centre for Clinical Neurosciences, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, United Kingdom.
Alessandro MagliDepartment of Medicine, Lillehei Heart Institute, Stem Cell Institute, University of Minnesota, Minneapolis, MN, United States.
Vincent MoulySorbonne Université, Inserm, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
Rita C R PerlingeiroDepartment of Medicine, Lillehei Heart Institute, Stem Cell Institute, University of Minnesota, Minneapolis, MN, United States.
Stefano C PrevitaliInSpe and Division of Neuroscience, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan, Italy.
Maurilio SampaolesiTranslational Cardiomyology Laboratory, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Hubert SmeetsDepartment of Toxicogenomics, Maastricht University Medical Centre, Maastricht, Netherlands.
Verena Schoewel-WolfMuscle Research Unit, Experimental and Clinical Research Center, a Cooperation Between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and the Charité, Universitätsmedizin Berlin, Berlin, Germany.
Simone SpulerMuscle Research Unit, Experimental and Clinical Research Center, a Cooperation Between the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association and the Charité, Universitätsmedizin Berlin, Berlin, Germany.
Yvan TorrenteUnit of Neurology, Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Centro Dino Ferrari, Università degli Studi di Milano, Fondazione Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Florence Van TienenDepartment of Toxicogenomics, Maastricht University Medical Centre, Maastricht, Netherlands.
Study Group
Max Delbrück Center · DECentre de Recherche en MyologieHenry Royce Institute · GBInstitut de Myologie · FRIRCCS Ospedale San Raffaele · ITMaastricht University · NLMaastricht University Medical Centre · NLManchester Academic Health Science Centre · GBManchester University NHS Foundation Trust · GBMinneapolis Heart Institute Foundation · USNational Institute for Health Research · GBUniversité de Rouen Normandie · FRUniversity of Milan · ITUniversity of Minnesota · USUniversity of Pavia · IT

Funding

Targeting Dystroglycanopathies using Pluripotent-derived Myogenic ProgenitorsR01AR071439 · NIAMS · UNIVERSITY OF MINNESOTA · PI PERLINGEIRO, RITA C. R. · 2017 to 2021
$1.9M
Medical Research Council MR/P016006/1Medical Research Council MR/S015116/1NIAMS NIH HHS R01 AR071439Wellcome Trust
6 · The paper itself

Abstract

This article will review myogenic cell transplantation for congenital and acquired diseases of skeletal muscle. There are already a number of excellent reviews on this topic, but they are mostly focused on a specific disease, muscular dystrophies and in particular Duchenne Muscular Dystrophy. There are also recent reviews on cell transplantation for inflammatory myopathies, volumetric muscle loss (VML) (this usually with biomaterials), sarcopenia and sphincter incontinence, mainly urinary but also fecal. We believe it would be useful at this stage, to compare the same strategy as adopted in all these different diseases, in order to outline similarities and differences in cell source, pre-clinical models, administration route, and outcome measures. This in turn may help to understand which common or disease-specific problems have so far limited clinical success of cell transplantation in this area, especially when compared to other fields, such as epithelial cell transplantation. We also hope that this may be useful to people outside the field to get a comprehensive view in a single review. As for any cell transplantation procedure, the choice between autologous and heterologous cells is dictated by a number of criteria, such as cell availability, possibility of

Indexed as

cell transplantationinflammatory myopathiesmitochondrial myopathiesmuscle stem cellsmuscular dystrophiessphincter incontinencevolumetric muscle loss

Identifiers

PMID34408774
PMCPMC8365145
OpenAlexW3193799043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.