Evidence map›Paper›PMID 34408755›Full record

ArticleFrontiers in immunology2021

Plasma C-Reactive Protein and Pentraxin-3 Reference Intervals During Normal Pregnancy.

Lina Wirestam, Sofia Pihl, Muna Saleh, Jonas Wetterö, Christopher Sjöwall

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. The Association of Prenatal C-Reactive Protein Levels With Childhood Asthma and Atopy.The journal of allergy and clinical immunology. In practice · 2022
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  14. [Epidemiological characterization of COVID-2019 in Mexican pregnant women: a cohort study].Revista medica del Instituto Mexicano del Seguro Social · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lina WirestamDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden.
Sofia PihlDepartment of Obstetrics and Gynaecology, Linköping University, Linköping, Sweden.
Muna SalehDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden.
Jonas WetteröDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden.
Christopher SjöwallDepartment of Biomedical and Clinical Sciences, Division of Inflammation and Infection/Rheumatology, Linköping University, Linköping, Sweden.
Linköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although several biomarkers are available to monitor the acute phase response, the short pentraxin C-reactive protein (CRP) is dominating in clinical practice. The long pentraxin 3 (PTX3) is structurally and functionally related to CRP, but not liver-derived. In addition, increased levels of PTX3 have been linked to preeclampsia. Reference intervals are usually based on healthy blood donors. Several physiological and immunological alterations occur during normal pregnancy with subsequent potential effects on blood analytes. Hence, this study aims to determine pregnancy-specific reference intervals for CRP and PTX3. Longitudinal clinical data and blood plasma samples from the 1

Indexed as

C-Reactive ProteinSerum Amyloid P-ComponentAdultBiomarkersEnzyme-Linked Immunosorbent AssayFemaleHumansPentraxinsPregnancyReference ValuesSerum Albumin, HumanYoung AdultBiomarkersC-Reactive ProteinPentraxinsSerum Albumin, HumanSerum Amyloid P-Componentacute phase proteinbiomarkersC-reactive proteininflammationpentraxin-3pregnancyreference interval (RI)

Identifiers

PMID34408755
PMCPMC8366313
OpenAlexW3191272640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.