Evidence map›Paper›PMID 34408754›Full record

ArticleFrontiers in immunology2021

Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the

Daniel V Lopez, Fatima A H Al-Jaberi, Nkerorema D Damas, Brian T Weinert, Urska Pus, Sara Torres-Rusillo, Anders Woetmann, Niels Ødum, Charlotte M Bonefeld, Martin Kongsbak-Wismann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  3. Autophagy andFrontiers in cellular and infection microbiology · 2026
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  7. Article
  8. Review
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  12. Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.International journal of molecular sciences · 2022
    Review
  13. Role of IL-22 in homeostasis and diseases of the skin.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Daniel V LopezThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Fatima A H Al-JaberiThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nkerorema D DamasThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.
Brian T WeinertThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.
Urska PusThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.
Sara Torres-RusilloThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Anders WoetmannThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Niels ØdumThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Charlotte M BonefeldThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Martin Kongsbak-WismannThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Carsten GeislerThe LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKTechnical University of Denmark · DKLEO Foundation · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Th22 cells constitute a recently described CD4

Indexed as

Promoter Regions, GeneticVitamin D Response ElementBasic Helix-Loop-Helix ProteinsBinding SitesBiomarkersCell LineCytokinesGene Expression RegulationHumansInflammation MediatorsInterleukin-22InterleukinsNuclear Receptor Subfamily 1, Group F, Member 3Nucleotide MotifsProtein BindingReceptors, Aryl HydrocarbonAHR protein, humanBasic Helix-Loop-Helix ProteinsBiomarkersCytokinesInflammation MediatorsInterleukin-22InterleukinsNuclear Receptor Subfamily 1, Group F, Member 3Receptors, Aryl HydrocarbonReceptors, CalcitriolVitamin DIL-17IL-22Th22 cellsvitamin Dvitamin D receptorvitamin D response element (VDRE)

Identifiers

PMID34408754
PMCPMC8366496
OpenAlexW3191696675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.