Evidence map›Paper›PMID 34408593›Full record

ArticlePostepy dermatologii i alergologii2021

Safety of bronchodilator reversibility test in elderly subjects: a prospective study.

Anna Dor-Wojnarowska, Anna Parużyńska, Aleksandra Kulczak, Marta Majewska-Pulsakowska, Małgorzata Szymala-Pędzik, Zbigniew Machaj, Małgorzata Sobieszczańska, Małgorzata Poręba

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anna Dor-WojnarowskaDepartment and Clinic of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, Poland.
Anna ParużyńskaDepartment and Clinic of Geriatrics, Wroclaw Medical University, Wroclaw, Poland.
Aleksandra KulczakDepartment and Clinic of Geriatrics, Wroclaw Medical University, Wroclaw, Poland.
Marta Majewska-PulsakowskaDepartment and Clinic of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, Poland.
Małgorzata Szymala-PędzikDepartment and Clinic of Geriatrics, Wroclaw Medical University, Wroclaw, Poland.
Zbigniew MachajDepartment and Clinic of Geriatrics, Wroclaw Medical University, Wroclaw, Poland.
Małgorzata SobieszczańskaDepartment and Clinic of Geriatrics, Wroclaw Medical University, Wroclaw, Poland.
Małgorzata PorębaDepartment of Pathophysiology, Wroclaw Medical University, Wroclaw, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe reversibility test measures an increase in ventilation parameters after the administration of 400 mg of a short-acting β-agonist (SABA). It is worth noting that a typical dosage, applied as a rescue medicine for bronchospastic dyspnoea, is significantly less, i.e., 100-200 mg.

aimTo assess the effects of inhaled 400 mg fenoterol (in the bronchodilator reversibility test) on the heart rate and the development of tachyarrhythmias in subjects aged 65 and above. MATERIAL AND

methodsA total of 53 subjects (45 women) aged 77; 68-82 (median; interquartile range) in stable clinical condition were included in the study. Data including medical history, physical examinations, blood biochemistry, chest X-ray, 12-lead electrocardiogram, 24-hour Holter ECG monitoring, bronchodilator test, and echocardiography were obtained. During the Holter ECG monitoring, the bronchodilator test using 400 mg fenoterol (Berotec pMDI) was performed.

resultsA slight but statistically significant (

conclusionsThe use of 400 mg fenoterol in a bronchodilator reversibility test in elderly subjects does not entail any significant cardiovascular risk.

Indexed as

24-hour Holter ECG monitoringbronchodilator testelderly subjects

Identifiers

PMID34408593
PMCPMC8362750
OpenAlexW3006713985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.