Evidence map›Paper›PMID 34408548›Full record

ReviewSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2021

Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives.

Swati Halder, Uttpal Anand, Samapika Nandy, Patrik Oleksak, Safaa Qusti, Eida M Alshammari, Gaber El-Saber Batiha, Eapen P Koshy, Abhijit Dey

Abstract readReview
In one paragraph

Review in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Molecules (Basel, Switzerland) · 2026
    Review
  5. iScience · 2026
    Article
  6. Pharmacological modulation of stress granulesFrontiers in pharmacology · 2026
    Review
  7. Review
  8. Review
  9. Protective Assessment of Novel (BNC Formulation) against Brain Tumor.Recent patents on anti-cancer drug discovery · 2025
    Article
  10. Evaluation of the Influence ofMolecules (Basel, Switzerland) · 2024
    Article
  11. Chemical Characterization and Assessment of the Neuroprotective Potential ofInternational journal of molecular sciences · 2024
    Article
  12. Article
  13. Review
  14. The Effects of Bioactive Compounds on Human Brain Structures and Diseases.International journal of molecular sciences · 2024
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Swati HalderDepartment of Life Sciences, Presidency University, 86/1 College Street, Kolkata 700073, West Bengal, India.
Uttpal AnandDepartment of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, Uttar Pradesh, India.
Samapika NandyDepartment of Life Sciences, Presidency University, 86/1 College Street, Kolkata 700073, West Bengal, India.
Patrik OleksakDepartment of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic.
Safaa QustiBiochemistry Department, Faculty of Science, king Abdulaziz University, Jeddah, Saudi Arabia.
Eida M AlshammariDepartment of Chemistry, College of Sciences, University of Ha'il, Ha'il, Saudi Arabia.
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Eapen P KoshyDepartment of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, Uttar Pradesh, India.
Abhijit DeyDepartment of Life Sciences, Presidency University, 86/1 College Street, Kolkata 700073, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory, one of the most vital aspects of the human brain, is necessary for the effective survival of an individual. 'Memory' can be defined in various ways but in an overall view, memory is the retention of the information that the brain grasps. Different factors are responsible for the disbalance in the brain's hippocampus region and the acetylcholine level, which masters the memory and cognitive functions. Plants are a source of pharmacologically potent drug molecules of high efficacy. Recently herbal medicine has evolved rapidly, gaining great acceptance worldwide due to their natural origin and fewer side effects. In this review, the authors have discussed the mechanisms and pharmacological action of herbal bioactive compounds to boost memory. Moreover, this review presents an update of different herbs and natural products that could act as memory enhancers and how they can be potentially utilized in the near future for the treatment of severe brain disorders. In addition, the authors also discuss the differences in biological activity of the same herb and emphasize the requirement for a higher standardization in cultivation methods and plant processing. The demand for further studies evaluating the interactions of herbal drugs is mentioned.

Indexed as

CognitionHerbal medicinesMemory enhancersMemory impairmentNootropicsPhytochemicals

Identifiers

PMID34408548
PMCPMC8363108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.