Evidence map›Paper›PMID 34408425›Full record

ArticleVascular health and risk management2021

Vitamin D and Its Metabolites Deficiency in Acute Coronary Syndrome Patients Undergoing Coronary Angiography: A Case-Control Study.

Hussein M Ismail, Abeer S Algrafi, Osama Amoudi, Sameh Ahmed, Sultan S Al-Thagfan, Hassan Shora, Mohammed Aljohani, Mohammed Almutairi, Fahad Alharbi, Abdullah Alhejaili and 3 more

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Hussein M IsmailDepartment of cardiology, College of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0001-9377-0749
Abeer S AlgrafiDepartment of medicine, College of Medicine, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Osama AmoudiMadinah Cardiac Center, Adult cardiology, Al-Madinah Al-Munawara, Saudi Arabia.
Sameh AhmedDepartment of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Sultan S Al-ThagfanDepartment of Clinical and Hospital Pharmacy, College of Pharmacy, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.ORCID 0000-0003-0144-9021
Hassan ShoraDepartment of molecular biology/biochemistry, Port Said University, Port Said, Egypt.ORCID 0000-0002-1958-8145
Mohammed AljohaniMedical intern, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Mohammed AlmutairiMedical intern, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Fahad AlharbiMedical intern, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Abdullah AlhejailiMedical intern, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Majed AlamriMedical intern, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Abdullah MuhawishMedical intern, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Ayat AbdallahEpidemiology and Preventive Medicine Department, National Liver Institute, Shebin El-Kom, Egypt.ORCID 0000-0002-5282-8614
Taibah University · SAIslamic University of Madinah · SAPort Said University · EGSuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D deficiency is considered an emerging health problem that affects at least one billion patients worldwide. Calcitriol 1,25(OH) MATERIALS AND

methodsThis was a case-control study on 73 consecutive adult patients with ACS undergoing coronary angiography compared to 50 controls without coronary artery disease and matched for age and sex from June 2019 till July 2019. Echocardiography and coronary angiography were done for all cases. Plasma vitamin D and its metabolites were measured at admission for all participants along with chemistry profiles.

resultsVitamin D and its metabolites were statistically significantly lower in ACS patients than the controls. Multivariate regression analysis revealed that low levels of 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)

conclusionThere was a strong association between vitamin D and all its metabolites with ACS. Significantly, low 25(OH)D and 1,25(OH)

Indexed as

Vitamin DAcute Coronary SyndromeAdultAgedAged, 80 and overCase-Control StudiesCholesterolCoronary AngiographyCoronary Artery DiseaseFemaleHumansMaleMiddle AgedStroke VolumeVentricular Function, LeftVitamin D Deficiency25-hydroxyvitamin DCholesterolVitamin D1,25-dihydroxyvitamin D325-hydroxyvitamin Dacute coronary syndromecoronary artery diseasevitamin D2vitamin D3

Identifiers

PMID34408425
PMCPMC8364363
OpenAlexW3192872992

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.