Evidence map›Paper›PMID 34408360›Full record

ReviewJournal of maxillofacial and oral surgery2021

Next-Generation Sequencing in Cancer.

S Vinod Nair, Madhulaxmi, Gigi Thomas, Ravindran Ankathil

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of maxillofacial and oral surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

S Vinod NairDepartment of Oral and Maxillofacial Surgery, P.M.S Dental College, Vattapara, Trivandrum, India.ORCID 0000-0002-0391-0152
MadhulaxmiDepartment of Oral and Maxillofacial Surgery, Saveetha Dental College, Chennai, India.
Gigi ThomasCommunity Medicine, Regional Cancer Centre, Trivandrum, India.
Ravindran AnkathilHuman Genome Centre, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, George Town, Malaysia.
Noorul Islam College of Dental Science · INRegional Cancer Center, Thiruvananthapuram · INSaveetha University · INUniversiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this article, we provide a gestalt idea about NGS technologies and their applications in cancer research and molecular diagnosis.

backgroundNext-generation sequencing (NGS) advancements like DNA sequencing and RNA sequencing allow uncovering of genomic, transcriptomic, and epigenomic scenes of individual malignant growths. An assortment of genomic abnormalities can be screened at the same time, for example common and uncommon variations, auxiliary variations like insertions and deletions, copy-number variation, and fusion transcripts.

conclusionNGS innovations together with bioinformatics investigation, which extend our insight, are progressively used to analyze multiple genes in a cost-effective way and have been applied in examining clinical cancer samples and offering NGS-based molecular diagnosis. APPLICATION: NGS is progressively significant as a device for the diagnosis of cancers.

Indexed as

CancerCancer researchMolecular diagnosisNext generation sequencingNGS

Identifiers

PMID34408360
PMCPMC8313644
OpenAlexW3093051138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.