Evidence map›Paper›PMID 34408351›Full record

ArticleJournal of obstetrics and gynaecology of India2021

Cervical Cancer Screening in HIV-Positive Women in India: Why, When and How?

Amulya Boddu, Neerja Bhatla, Shachi Vashist, Sandeep Mathur, Reeta Mahey, Jayashree Natarajan, Ria Malik, Perumal Vanamail, Shweta Rai, Aruna Kumari and 2 more

Abstract read
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amulya BodduDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Neerja BhatlaDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.ORCID 0000-0002-3894-2795
Shachi VashistDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Sandeep MathurDepartment of Pathology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Reeta MaheyDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Jayashree NatarajanDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Ria MalikDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Perumal VanamailDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Shweta RaiDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Aruna KumariDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Lalit DarDepartment of Microbiology, All India Institute of Medical Sciences AIIMS, New Delhi, India.
Naveet WigDepartment of Medicine, All India Institute of Medical Sciences AIIMS, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical cancer is an AIDS-defining illness, and HIV-positive women are at high risk. The present study aimed to determine the magnitude of the problem, compare the performance of screening tests and assess factors affecting participation.

methodsHIV-positive women aged 30-59 years attend the anti-retroviral therapy (ART) clinics were screened by conventional Pap, HPV testing (Hybrid Capture 2) and visual inspection with acetic acid (VIA). A cohort of HIV-negative women from the community matched for age and parity were screened similarly. Screen-positive women underwent colposcopy and biopsy. Factors affecting participation were assessed.

resultsPap, VIA and HPV were positive in 48 (23.8%), 65 (32.2%) and 76 (37.6%) subjects, respectively, among HIV-positive women, and in 12 (5.9%), 10 (4.9%) and 12 (5.9%) subjects, respectively, among HIV-negative women

conclusionsThere was higher prevalence of HPV infection and CIN2 + lesions in HIV-positive women. VIA showed equivalent sensitivity to Pap and could be a good substitute in low resource settings. Setting up cervical screening services in ART clinics and sensitising physicians can improve outcomes among these women.

Indexed as

BarriersCervical cancerCINColposcopyHIVPapScreeningVIA

Identifiers

PMID34408351
PMCPMC8310826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.