Evidence map›Paper›PMID 34408320›Full record

ArticleNature2021

Molecular basis for DarT ADP-ribosylation of a DNA base.

Marion Schuller, Rachel E Butler, Antonio Ariza, Callum Tromans-Coia, Gytis Jankevicius, Tim D W Claridge, Sharon L Kendall, Shan Goh, Graham R Stewart, Ivan Ahel

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Prokaryotic homeostasis - a solution to thrive and survive.Frontiers in molecular biosciences · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Deregulated DNA ADP-ribosylation impairs telomere replication.Nature structural & molecular biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Marion SchullerSir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Rachel E ButlerDepartment of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, UK.
Antonio ArizaSir William Dunn School of Pathology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-4364-823X
Callum Tromans-CoiaSir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Gytis JankeviciusSir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Tim D W ClaridgeDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-5583-6460
Sharon L KendallCentre for Emerging, Endemic and Exotic Disease, Pathology and Population Sciences, The Royal Veterinary College, Hatfield, UK.ORCID http://orcid.org/0000-0003-3277-3035
Shan GohCentre for Emerging, Endemic and Exotic Disease, Pathology and Population Sciences, The Royal Veterinary College, Hatfield, UK.
Graham R StewartDepartment of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, UK. g.stewart@surrey.ac.uk.ORCID http://orcid.org/0000-0002-6867-6248
Ivan AhelSir William Dunn School of Pathology, University of Oxford, Oxford, UK. ivan.ahel@path.ox.ac.uk.ORCID http://orcid.org/0000-0002-9446-3756
University of Oxford · GBRoyal Veterinary College · GBUniversity of Surrey · GBUniversity of Basel · CH

Funding

Cancer Research UK 22284
6 · The paper itself

Abstract

ADP-ribosyltransferases use NAD

Indexed as

ADP-RibosylationAdenosine Diphosphate RiboseAntitoxinsBacterial ProteinsBacterial ToxinsBase SequenceBiocatalysisDNADNA AdductsDNA, BacterialDNA DamageDNA RepairDNA Transposable ElementsModels, MolecularMycobacteriumNitrogenAdenosine Diphosphate RiboseAntitoxinsBacterial ProteinsBacterial ToxinsDNADNA AdductsDNA, BacterialDNA Transposable ElementsNitrogenPoly(ADP-ribose) PolymerasesThymidineThymine

Identifiers

PMID34408320
OpenAlexW3193708947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.