ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2022
The role of prefrontal cortex in cognitive control and executive function.
Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 866 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Frontal E/I Balance Mediation of tACS Effects on Behavioral Flexibility
The Effectiveness of Mindfulness-based Relapse Prevention: A Randomized Controlled Trial Study
Who cites it
866 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Dose-response relationship between exercise interventions and motor skills in children with autism spectrum disorder: a systematic review and multilevel meta-analysis.European journal of pediatrics · 2026Pooled it
- Efficacy of different exercise interventions on cognitive function in adults with major depressive disorder and subthreshold depression: a systematic review with pairwise and network meta-analyses.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- Sorting the mind: cognitive enhancement through transcutaneous auricular vagus nerve stimulation: a systematic review and meta-analysis.Psychological medicine · 2026Pooled it
- Transdiagnostic mapping of brain structural abnormalities and network-constrained gray matter atrophy patterns across affective and psychotic disorders.Molecular psychiatry · 2026Pooled it
- What type of exercise prescription is best for improving cognitive flexibility in children and adolescents? A network meta-analysis.BMC psychology · 2026Pooled it
- Effects of whole-body vibration on cognitive function: a systematic review and meta-analysis.GeroScience · 2026Pooled it
- Potential Targets for Scalp Acupuncture and Brain Stimulation in Mental Disorders: Evidence From Large-Scale Meta-Analyses.Alpha psychiatry · 2026Pooled it
- Chronic mind-body exercises for executive functions in middle-aged and older adults: a systematic review and meta-analysis of randomized controlled trials.Aging clinical and experimental research · 2026Pooled it
- The analysis of the prefrontal cortex and its facilitator role of violence: conclusions of a systematic review and meta-analysis based on neuroimaging results.Brain imaging and behavior · 2026Pooled it
- Effectiveness of the Hayling and Brixton Tests for Detecting Dementia, Progressive Cognitive Decline, and Mild Cognitive Impairment in Middle to Older Aged Adults: A Systematic Review and Meta-analysis.Neuropsychology review · 2026Pooled it
- Molecular and topographic mapping of antipsychotic effects: a meta-analysis of postsynaptic density proteins in animal models with translational implications.Molecular psychiatry · 2026Pooled it
- Neurocognitive Profiles and Predictors of Symptom Trajectory During and After Treatment in Adolescent Bulimia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2026Trial
- Comparative efficacy of dual- vs. single-node tACS in amnestic mild cognitive impairment: behavioral and EEG evidence.Translational psychiatry · 2026Trial
- Trial
- The functional neuroanatomy of event-based and time-based prospective memory, and its improvement.Communications biology · 2026Trial
- Effects of traditional culture picture book intervention on emotional regulation ability and neuropsychology of preschool children.Frontiers in public health · 2026Trial
- Factors associated with executive function in children with lymphoma undergoing chemotherapy: A cross-sectional study based on the theory of unpleasant symptoms.Asia-Pacific journal of oncology nursing · 2026Article
- Hierarchical disruption of lateral prefrontal cortex gradients in cognitive aging.GeroScience · 2026Article
- Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias.Current research in neurobiology · 2026Article
- Factors associated with the risk of falls and their relationship with cognitive function in older adults with cognitive impairment: a cross-sectional study.GeroScience · 2026Article
806 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Concepts of cognitive control (CC) and executive function (EF) are defined in terms of their relationships with goal-directed behavior versus habits and controlled versus automatic processing, and related to the functions of the prefrontal cortex (PFC) and related regions and networks. A psychometric approach shows unity and diversity in CC constructs, with 3 components in the most commonly studied constructs: general or common CC and components specific to mental set shifting and working memory updating. These constructs are considered against the cellular and systems neurobiology of PFC and what is known of its functional neuroanatomical or network organization based on lesioning, neurochemical, and neuroimaging approaches across species. CC is also considered in the context of motivation, as "cool" and "hot" forms. Its Common CC component is shown to be distinct from general intelligence (g) and closely related to response inhibition. Impairments in CC are considered as possible causes of psychiatric symptoms and consequences of disorders. The relationships of CC with the general factor of psychopathology (p) and dimensional constructs such as impulsivity in large scale developmental and adult populations are considered, as well as implications for genetic studies and RDoC approaches to psychiatric classification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.