Evidence map›Paper›PMID 34408242›Full record

ArticleCommunications biology2021

The development and structure of the mesentery.

Kevin G Byrnes, Dara Walsh, Leon G Walsh, Domhnall M Coffey, Muhammad F Ullah, Rosa Mirapeix, Jill Hikspoors, Wouter Lamers, Yi Wu, Xiao-Qin Zhang and 12 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. The mesenteric model of abdominal anatomy.Nature reviews. Gastroenterology & hepatology · 2026
    Article
  2. Review
  3. Article
  4. The Surgical Management of the Mesentery in Crohn's Disease.Clinics in colon and rectal surgery · 2025
    Review
  5. Article
  6. The Mesentery's Pivotal Role in the Brain-Gut-Liver Axis.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. The Development of the Mesenteric Model of Abdominal Anatomy.Clinics in colon and rectal surgery · 2022
    Review
  12. The Mesentery-Past, Present, and Future.Clinics in colon and rectal surgery · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 4 countries.

Kevin G ByrnesDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Dara WalshDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.ORCID 0000-0002-4962-9809
Leon G WalshDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Domhnall M CoffeyDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Muhammad F UllahDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Rosa MirapeixDepartment of Anatomy and Embryology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Jill HikspoorsDepartment of Anatomy and Embryology, Maastricht University, Maastricht, Netherlands.ORCID 0000-0003-2940-1812
Wouter LamersDepartment of Anatomy and Embryology, Maastricht University, Maastricht, Netherlands.ORCID 0000-0003-3032-7824
Yi WuDigital Medicine Department, Biomedical Engineering College, Third Military Medical University, Chongqing, China.
Xiao-Qin ZhangDigital Medicine Department, Biomedical Engineering College, Third Military Medical University, Chongqing, China.
Shao-Xiang ZhangDigital Medicine Department, Biomedical Engineering College, Third Military Medical University, Chongqing, China.
Pieter BramaSchool of Veterinary Medicine, Veterinary Science Centre, Dublin, Ireland.
Colum P Dunne4iCentre for Interventions in Infection, Inflammation and Immunology, School of Medicine, University of Limerick, Limerick, Ireland.ORCID 0000-0002-5010-3185
Ian S O'BrienDepartment of Anatomy, National University of Ireland Galway, Galway, Ireland.
Colin B PeirceDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Martin J ShellyDepartment of Radiology, University of Limerick Hospitals Group, Limerick, Ireland.
Tim G ScanlonDepartment of Radiology, University of Limerick Hospitals Group, Limerick, Ireland.
Mary E LutherDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Hugh D BradyDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland.
Peter DockeryDepartment of Anatomy, National University of Ireland Galway, Galway, Ireland.
Kieran W McDermott4iCentre for Interventions in Infection, Inflammation and Immunology, School of Medicine, University of Limerick, Limerick, Ireland.
J Calvin CoffeyDepartment of Surgery, University of Limerick Hospitals Group, Limerick, Ireland. calvin.coffey@ul.ie.ORCID 0000-0003-0007-8206
University of Limerick · IEArmy Medical University · CNMaastricht University · NLOllscoil na Gaillimhe – University of Galway · IEUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The position of abdominal organs, and mechanisms by which these are centrally connected, are currently described in peritoneal terms. As part of the peritoneal model of abdominal anatomy, there are multiple mesenteries. Recent findings point to an alternative model in which digestive organs are connected to a single mesentery. Given that direct evidence of this is currently lacking, we investigated the development and shape of the entire mesentery. Here we confirm that, within the abdomen, there is one mesentery in which all abdominal digestive organs develop and remain connected to. We show that all abdominopelvic organs are organised into two, discrete anatomical domains, the mesenteric and non-mesenteric domain. A similar organisation occurs across a range of animal species. The findings clarify the anatomical foundation of the abdomen; at the foundation level, the abdomen comprises a visceral (i.e. mesenteric) and somatic (i.e. musculoskeletal) frame. The organisation at that level is a fundamental order that explains the positional anatomy of all abdominopelvic organs, vasculature and peritoneum. Collectively, the findings provide a novel start point from which to systemically characterise the abdomen and its contents.

Indexed as

HumansMesenteryPeritoneum

Identifiers

PMID34408242
PMCPMC8373875
OpenAlexW3194397926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.