Evidence map›Paper›PMID 34408208›Full record

ArticleScientific reports2021

Bone conducted responses in the neonatal rat auditory cortex.

Roman Makarov, Mikhail Sintsov, Guzel Valeeva, Pavel Starikov, Dmitriy Negrov, Roustem Khazipov

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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  8. Nuclear Translocation Triggered at the Onset of Hearing in Cochlear Inner Hair Cells of Rats and Mice.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Roman MakarovLaboratory of Neurobiology, Kazan Federal University, Kazan, Russia, 420008.
Mikhail SintsovLaboratory of Neurobiology, Kazan Federal University, Kazan, Russia, 420008.
Guzel ValeevaLaboratory of Neurobiology, Kazan Federal University, Kazan, Russia, 420008.
Pavel StarikovThe School of Electronics, Photonics and Molecular Physics, Moscow Institute of Physics and Technology, Moscow, Russia, 117303.
Dmitriy NegrovThe School of Electronics, Photonics and Molecular Physics, Moscow Institute of Physics and Technology, Moscow, Russia, 117303.
Roustem KhazipovLaboratory of Neurobiology, Kazan Federal University, Kazan, Russia, 420008. roustem.khazipov@inserm.fr.
Kazan Federal University · RUMoscow Institute of Physics and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rats are born deaf and start hearing at the end of the second postnatal week, when the ear canals open and low-intensity sounds start to evoke responses in the auditory cortex. Here, using μECoG electrode arrays and intracortical silicon probe recordings, we found that bone-conducted (BC) sounds evoked biphasic responses in the auditory cortex starting from postnatal day (P) 8. The initial phase of these responses, generated by thalamocortical input, was followed by intracortical propagation within supragranular layers. BC-evoked responses co-localized with the responses evoked by electrical stimulation of the cochlea and the deepest layers of the inferior colliculus prior to onset of low-threshold hearing (P13), as well as with the responses evoked by high-frequency (30 kHz) low-intensity (70 dB) air-conducted sounds after that. Thus, BC signals reach high-frequency processing regions of the auditory cortex well before the onset of low-threshold hearing, reflecting early integrity of the auditory system.

Indexed as

AnimalsAnimals, NewbornAuditory CortexBone ConductionCochleaElectric StimulationInferior ColliculiRatsRats, Wistar

Identifiers

PMID34408208
PMCPMC8373948
OpenAlexW3133205992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.