ArticleScientific reports2021
Dissociation of structural and functional connectomic coherence in glioma patients.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Unveiling the whole-brain impact of diffuse midline glioma: cortical morphological remodeling and network alterations driven by H3 K27 mutation.Neuroradiology · 2026Article
- Anomaly Detection for Structural and Functional Connectivity in Glioma Patients.NMR in biomedicine · 2026Article
- Standard craniotomy under general anesthesia with bridging vein-guided tailored transcortical resection for medial frontal glioma involving the cingulate gyrus: A case report.Surgical neurology international · 2026Article
- Structural-functional fingerprinting for abnormalities investigation in glioma patients.Scientific reports · 2025Article
- High peritumoral network connectedness in glioblastoma reveals a distinct epigenetic signature and is associated with decreased overall survival.Neuro-oncology · 2025Article
- Review
- Tumor resting-state fMRI connectivity to extralesional brain is associated with cognitive performance in glioma patients.Brain & spine · 2025Article
- Epilepsy alters brain networks in patients with insular glioma.CNS neuroscience & therapeutics · 2024Article
- A prognostic neural epigenetic signature in high-grade glioma.Nature medicine · 2024Article
- Cortical myelin and thickness mapping provide insights into whole-brain tumor burden in diffuse midline glioma.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Predicting survival in glioblastoma with multimodal neuroimaging and machine learning.Journal of neuro-oncology · 2023Article
- Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability.bioRxiv : the preprint server for biology · 2023Article
- The dynamic functional connectivity fingerprint of high-grade gliomas.Scientific reports · 2023Article
- Controllability and Robustness of Functional and Structural Connectomic Networks in Glioma Patients.Cancers · 2023Article
- Structural alterations of the salience network in patients with insular glioma.Brain and behavior · 2023Article
- Self-Referential Processing and Resting-State Functional MRI Connectivity of Cortical Midline Structures in Glioma Patients.Brain sciences · 2022Article
- Should Neurosurgeons Try to Preserve Non-Traditional Brain Networks? A Systematic Review of the Neuroscientific Evidence.Journal of personalized medicine · 2022Review
- What Can Resting-State fMRI Data Analysis Explain about the Functional Brain Connectivity in Glioma Patients?Tomography (Ann Arbor, Mich.) · 2022Review
- Structural Brain Network Reorganization Following Anterior Callosotomy for Colloid Cysts: Connectometry and Graph Analysis Results.Frontiers in neurology · 2022Article
- Alternations and Applications of the Structural and Functional Connectome in Gliomas: A Mini-Review.Frontiers in neuroscience · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With diffuse infiltrative glioma being increasingly recognized as a systemic brain disorder, the macroscopically apparent tumor lesion is suggested to impact on cerebral functional and structural integrity beyond the apparent lesion site. We investigated resting-state functional connectivity (FC) and diffusion-MRI-based structural connectivity (SC) (comprising edge-weight (EW) and fractional anisotropy (FA)) in isodehydrogenase mutated (IDHmut) and wildtype (IDHwt) patients and healthy controls. SC and FC were determined for whole-brain and the Default-Mode Network (DMN), mean intra- and interhemispheric SC and FC were compared across groups, and partial correlations were analyzed intra- and intermodally. With interhemispheric EW being reduced in both patient groups, IDHwt patients showed FA decreases in the ipsi- and contralesional hemisphere, whereas IDHmut patients revealed FA increases in the contralesional hemisphere. Healthy controls showed strong intramodal connectivity, each within the structural and functional connectome. Patients however showed a loss in structural and reductions in functional connectomic coherence, which appeared to be more pronounced in IDHwt glioma patients. Findings suggest a relative dissociation of structural and functional connectomic coherence in glioma patients at the time of diagnosis, with more structural connectomic aberrations being encountered in IDHwt glioma patients. Connectomic profiling may aid in phenotyping and monitoring prognostically differing tumor types.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.