Evidence map›Paper›PMID 34408190›Full record

ArticleScientific reports2021

Anatomy of Cowper's gland in humans suggesting a secretion and emission mechanism facilitated by cooperation of striated and smooth muscles.

Satoru Muro, Janyaruk Suriyut, Keiichi Akita

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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  5. MR imaging of penile pathology and prostheses.Abdominal radiology (New York) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Satoru MuroDepartment of Clinical Anatomy, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. muro.fana@tmd.ac.jp.
Janyaruk SuriyutDepartment of Anatomy, Faculty of Medicine, Srinakharinwirot University, Bangkok, 10110, Thailand.
Keiichi AkitaDepartment of Clinical Anatomy, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Tokyo Medical and Dental University · JPSrinakharinwirot University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the detailed anatomy of the Cowper's gland in humans. Elucidating the mechanism of secretion and emission of the Cowper's gland requires analysis of the muscles around the Cowper's gland. We hypothesized that the Cowper's gland involves not only smooth muscle but also the striated muscles of the pelvic floor. Here, we provide comprehensive and three-dimensional anatomy of the Cowper's gland and its surrounding structures, which overcomes the current local and planar understanding. In this study, seven male corpses of body donors were used to conduct macroscopic anatomy, histology, and three-dimensional reconstruction. The Cowper's gland was surrounded laterally and posterosuperiorly by striated and smooth muscles, respectively. The striated muscle bundle was connected from the superficial transverse perineal muscle, levator ani, and external anal sphincter to the external urethral sphincter (rhabdosphincter). The smooth muscle was part of the deep transverse perineal muscle and entered between the bilateral Cowper's glands and lobules. Our findings indicate that the secretion and emission of the Cowper's gland in humans are carried out through the cooperation of striated and smooth muscles.

Indexed as

AgedAged, 80 and overBulbourethral GlandsHumansMaleMiddle AgedMuscle, SmoothMuscle, StriatedUrethra

Identifiers

PMID34408190
PMCPMC8373982
OpenAlexW3194237843

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.