ArticleScientific reports2021
Identification and antimicrobial susceptibility profiles of Nocardia species clinically isolated in Japan.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outcomes and treatment for disseminated nocardiosis caused by Nocardia otitidiscaviarum: a systematic review.BMC infectious diseases · 2026Pooled it
- Species-level identification of Nocardia spp. from clinical samples via intelligent analysis of Raman spectroscopic fingerprints.World journal of microbiology & biotechnology · 2026Article
- Successful Treatment with Surgical Resection for Nocardia cyriacigeorgica Infection in Pulmonary Sequestration.Internal medicine (Tokyo, Japan) · 2026Article
- Disseminated Nocardia brasiliensis causing septic arthritis in a patient with non-small cell lung adenocarcinoma: a case report.BMC infectious diseases · 2026Article
- A Case of Disseminated Nocardiosis due toRespirology case reports · 2026Article
- Clinical and microbiological characteristics of Nocardia infections: a 10-Year multicentre study from Türkiye.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Article
- A landscape of epidemiology and strain distribution ofBiosafety and health · 2026Article
- NCY-1 β-Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica.MicrobiologyOpen · 2026Article
- Pulmonary Nocardia otitidiscaviarum in immunocompetent individuals: a case series and literature review.BMC infectious diseases · 2026Review
- Epidemiology, clinical treatment and outcomes, susceptibility patterns and genotypic analysis of 214Frontiers in cellular and infection microbiology · 2026Article
- Research progress on clinical challenges and prevention strategies of drug-resistantFrontiers in public health · 2026Review
- Phylogenetic and Genomic Feature Analysis of CutaneousInfection and drug resistance · 2026Article
- Article
- A Rare Case of DisseminatedInfectious disease reports · 2025Article
- Microbial spectrum and emerging antibiotic sensitivity patterns in explanted scleral buckle elements-a 12 year retrospective analysis.International ophthalmology · 2025Observational
- Cutaneous nocardiosis in chronic renal insufficiency: Diagnostic and therapeutic considerations.World journal of clinical cases · 2025Article
- Population-based microbiological characterization ofMicrobiology spectrum · 2025Article
- Genomic characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic insights into Nocardia cyriacigeorgica.Annals of clinical microbiology and antimicrobials · 2025Article
- Case Report: Nanopore Sequencing-Based Detection of Pulmonary Nocardiosis Caused by Nocardia Otitidiscaviarum in an Immunocompetent Patient.Infection and drug resistance · 2025Article
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The aims of the present study were to profile the antimicrobial susceptibility patterns of a diverse range of Nocardia species isolated in Japan, and to determine the ability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for species/complex identification. Identification of 153 clinical isolates was performed by full-length 16S rRNA gene sequencing as a reference method to evaluate the usefulness of MALDI-TOF MS identification. Antimicrobial susceptibility testing (AST) for 14 antibiotics was performed using the broth microdilution method against 146 of the isolates. Among the total 153 clinical isolates, Nocardia farcinica complex (25%) was the most common species, followed by Nocardia cyriacigeorgica (18%), Nocardia brasiliensis (9%), Nocardia nova (8%), and Nocardia otitidiscaviarum (7%). Among 150 isolates identified to the species/complex level by 16S rRNA gene sequencing, MALDI-TOF MS with the use of a supplemental Nocardia library (JMLD library ver.ML01) correctly identified 97.3% (n = 146) to the species/complex level and 1.3% (n = 2) to the genus level. Among the 146 Nocardia isolates that underwent AST, the susceptibilities were 100% to linezolid, 96% to amikacin, 94% to trimethoprim-sulfamethoxazole, and 76% to imipenem. None of the trimethoprim-sulfamethoxazole-resistant isolates carried either plasmid-mediated sulfonamide-resistant genes (sul1, sul2) or trimethoprim-resistant genes (dfrA).
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