Evidence map›Paper›PMID 34408167›Full record

ArticleScientific reports2021

Neighbors-based prediction of physical function after total knee arthroplasty.

Chong Kim, Kathryn L Colborn, Stef van Buuren, Timothy Loar, Jennifer E Stevens-Lapsley, Andrew J Kittelson

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chong KimDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Aurora, CO, USA.
Kathryn L ColbornDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Aurora, CO, USA.
Stef van BuurenNetherlands Organization for Applied Scientific Research TNO, Leiden, The Netherlands.
Timothy LoarPhysical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado, Aurora, CO, USA.
Jennifer E Stevens-LapsleyPhysical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado, Aurora, CO, USA.
Andrew J KittelsonPhysical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado, Aurora, CO, USA. Andy.Kittelson@umontana.edu.

Funding

MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
Novel Strategies for Personalized Clinical Decisions in Knee ArthroplastyR01HS025692 · AHRQ · UNIVERSITY OF COLORADO DENVER · PI STEVENS-LAPSLEY, JENNIFER E. · 2018 to 2022
$1.8M
Developing Individualized Estimates of Patient Prognosis Following Knee ReplacementR03HS024316 · AHRQ · UNIVERSITY OF COLORADO DENVER · PI STEVENS-LAPSLEY, JENNIFER E. · 2016 to 2017
$100k
AHRQ HHS R01 HS025692AHRQ HHS R03 HS024316NICHD NIH HHS K12 HD055931
6 · The paper itself

Abstract

The purpose of this study was to develop and test personalized predictions for functional recovery after Total Knee Arthroplasty (TKA) surgery, using a novel neighbors-based prediction approach. We used data from 397 patients with TKA to develop the prediction methodology and then tested the predictions in a temporally distinct sample of 202 patients. The Timed Up and Go (TUG) Test was used to assess physical function. Neighbors-based predictions were generated by estimating an index patient's prognosis from the observed recovery data of previous similar patients (a.k.a., the index patient's "matches"). Matches were determined by an adaptation of predictive mean matching. Matching characteristics included preoperative TUG time, age, sex and Body Mass Index. The optimal number of matches was determined to be m = 35, based on low bias (- 0.005 standard deviations), accurate coverage (50% of the realized observations within the 50% prediction interval), and acceptable precision (the average width of the 50% prediction interval was 2.33 s). Predictions were well-calibrated in out-of-sample testing. These predictions have the potential to inform care decisions both prior to and following TKA surgery.

Indexed as

Arthroplasty, Replacement, KneeKnee JointModels, BiologicalOsteoarthritis, KneeRecovery of FunctionAgedFemaleHumansMaleMiddle AgedPredictive Value of Tests

Identifiers

PMID34408167
PMCPMC8373960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.