Evidence map›Paper›PMID 34408164›Full record

ArticleScientific reports2021

Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma.

Eleni Costa, Babatunde O Okesola, Christopher Thrasivoulou, David L Becker, Jan A Deprest, Anna L David, Tina T Chowdhury

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Role of Myofibroblasts in Physiological and Pathological Tissue Repair.Cold Spring Harbor perspectives in biology · 2023
    Review
  7. The extended analogy of extraembryonic development in insects and amniotes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Eleni CostaInstitute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.
Babatunde O OkesolaInstitute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.
Christopher ThrasivoulouDepartment of Cell and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, UK.
David L BeckerLee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, Singapore.
Jan A DeprestDepartment of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium.
Anna L DavidDepartment of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium.
Tina T ChowdhuryInstitute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London, E1 4NS, UK. t.t.chowdhury@qmul.ac.uk.
Queen Mary University of London · GBKU Leuven · BENanyang Technological University · SGUniversity College London · GB

Funding

Department of Health
6 · The paper itself

Abstract

The wound healing capacity of the fetal membranes after spontaneous or iatrogenic membrane rupture is unclear. We examined the healing mechanisms in amniotic membrane (AM) defects after trauma. Traumatised human AM defects were cultured for 4 days. Markers for nuclear (DAPI), cell type (vimentin, αSMA) and healing (Cx43, TGFβ

Indexed as

AmnionCollagenConnexin 43Extraembryonic MembranesFemaleHumansMyofibroblastsPregnancyPremature Rupture of Fetal MembranesVimentinWound HealingCollagenConnexin 43GJA1 protein, humanVimentin

Identifiers

PMID34408164
PMCPMC8373966
OpenAlexW3196073892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.