Evidence map›Paper›PMID 34408075›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Genomic structural variants constrain and facilitate adaptation in natural populations of

Tuomas Hämälä, Eric K Wafula, Mark J Guiltinan, Paula E Ralph, Claude W dePamphilis, Peter Tiffin

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Inversion characterization inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Multi-variant GWAS and genomic prediction dissect the genetic architecture underlying tomato fruit weight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  6. Article
  7. Structural Variation and Its Roles in Plant Genomes.Plants (Basel, Switzerland) · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
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  13. Article
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  15. Article
  16. The pangenome ofiScience · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tuomas HämäläDepartment of Plant and Microbial Biology, University of Minnesota, St. Paul, MN 55108; tuomas.hamala@gmail.com ptiffin@umn.edu.ORCID 0000-0001-8306-3397
Eric K WafulaDepartment of Biology, The Pennsylvania State University, University Park, PA 16802.
Mark J GuiltinanDepartment of Plant Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-0018-9846
Paula E RalphDepartment of Biology, The Pennsylvania State University, University Park, PA 16802.
Claude W dePamphilisDepartment of Biology, The Pennsylvania State University, University Park, PA 16802.
Peter TiffinDepartment of Plant and Microbial Biology, University of Minnesota, St. Paul, MN 55108; tuomas.hamala@gmail.com ptiffin@umn.edu.ORCID 0000-0003-1975-610X
Pennsylvania State University · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic structural variants (SVs) can play important roles in adaptation and speciation. Yet the overall fitness effects of SVs are poorly understood, partly because accurate population-level identification of SVs requires multiple high-quality genome assemblies. Here, we use 31 chromosome-scale, haplotype-resolved genome assemblies of

Indexed as

Adaptation, PhysiologicalChocolateGenome, PlantGenomic Structural VariationBiological EvolutionCacaoChromosomes, PlantPhenotypePlant BreedingTreescacaode novo assemblygenetic loadlocal adaptationstructural variants

Identifiers

PMID34408075
PMCPMC8536383
OpenAlexW3194408081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.