SynthesisBMJ open2021
Association between fasting blood glucose levels and stroke events: a large-scale community-based cohort study from China.
Synthesis in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The effect of community intervention based on deep learning-established early screening system and model construction for stroke.BMC neurology · 2026Article
- Plasma Tryptophan Hydroxylase 1 Activity-related Metabolic Markers and Stroke Risk: A Nested Case-control Study.Translational stroke research · 2026Article
- Glucose tolerance phenotypes and risks of incident first-ever stroke and all-cause mortality in low-income rural Chinese adults: a population-based prospective cohort study.Frontiers in endocrinology · 2026Article
- Association of cholesterol, high-density lipoprotein, and glucose index and its modified indices with the risk of stroke: insights from CHARLS.BMC neurology · 2025Article
- Fasting plasma glucose trajectories are associated with ischemic stroke in the elderly: a longitudinal study using group-based trajectory modeling in Chinese communities.BMC public health · 2025Article
- Clinical value of Lp-PLA2, LDL-C, HDL-C, hs-CRP, leukocyte, FPG and HbA1c in type 2 diabetes mellitus patients with acute ischemic stroke.Frontiers in endocrinology · 2025Article
- Metabolic syndrome parameters' variability and stroke incidence in hypertensive patients: evidence from a functional community cohort.Cardiovascular diabetology · 2024Article
- The Tryptophan Index Is Associated with Risk of Ischemic Stroke: A Community-Based Nested Case-Control Study.Nutrients · 2024Article
- Health literacy, self-efficacy, self-care behaviors, and glycemic control among older adults with type 2 diabetes mellitus: a cross-sectional study in Thai communities.BMC geriatrics · 2023Article
- The stress hyperglycemia ratio is associated with the development of cerebral edema and poor functional outcome in patients with acute cerebral infarction.Frontiers in aging neuroscience · 2022Article
- The link between sleep duration and stroke risk.Brain circulationArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDiabetes mellitus has been associated with stroke. However, the association between fasting blood glucose (FBG) and stroke risk in a general population remains not clear. The purpose of our study was to examine the FBG levels on subsequent stroke risk in a community-based cohort in China.
designProspective cohort study, employing Cox proportional hazard model to analyse the association of FBG levels with stroke risk.
settingA community-based cohort study included adults participating in a baseline survey conducted in 2013 in Changshu, eastern China.
participants16 113 participants were recruited with a multistage sampling method, excluding participants with severe disability, severe cancer, severe psychiatric disturbance or previous stroke before enrolment. PRIMARY OUTCOME MEASURES: Stroke events.
resultsDuring a median follow-up of 5.5 years, 417 incident cases of stroke were identified. The adjusted HR for total and ischaemic stroke for participants in the fourth quartile of FBG compared with the first quartile was 1.44 (95% CI 1.07 to 1.94) and 1.57 (95% CI 1.11 to 2.21), respectively. FBG levels of ≥7.0 mmol/L were associated with an increased risk of stroke based on two clinical classifications (American Diabetes Association: 1.68 (1.24 to 2.27); WHO: 1.62 (1.21, 2.13)). In stratified analyses, risk associations existed in women (HR: 1.92, 95% CI 1.22 to 3.01) and postmenopausal women (HR: 1.68, 95% CI 1.06 to 2.68) for the fourth quartile versus the first. More importantly, the meta-analysis observed a positive association between FBG levels and stroke risk (pooled HR: 1.70, 95% CI 1.27 to 2.29; n=7)).
conclusionsHigher FBG level was independently associated with an increased risk of stroke in Chinese adults, especially significant in women.
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