Evidence map›Paper›PMID 34407948›Full record

ArticleScience advances2021

Reservoir computing with biocompatible organic electrochemical networks for brain-inspired biosignal classification.

Matteo Cucchi, Christopher Gruener, Lautaro Petrauskas, Peter Steiner, Hsin Tseng, Axel Fischer, Bogdan Penkovsky, Christian Matthus, Peter Birkholz, Hans Kleemann and 1 more

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Intrinsic Disordered Network in Multiferroic YMnOSmall (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Brain-Inspired Polymer Dendrite Networks for Morphology-Dependent Computing Hardware.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  17. Versatile and Robust Reservoir Computing with PWM-Driven Heterogenous R-C Circuits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matteo CucchiDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany. matteo.cucchi@tu-dresden.de.ORCID http://orcid.org/0000-0002-5400-5793
Christopher GruenerDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany.
Lautaro PetrauskasDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany.ORCID http://orcid.org/0000-0002-0516-8326
Peter SteinerInstitute for Acoustics and Speech Communication (IAS), Technische Universität Dresden, Helmholtzstr. 18, 01069 Dresden, Germany.
Hsin TsengDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany.
Axel FischerDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany.
Bogdan PenkovskyNational University of Kyiv-Mohyla Academy, Skovorody Str. 2, 04655 Kyiv, Ukraine.ORCID http://orcid.org/0000-0003-1851-0415
Christian MatthusChair for Circuit Design and Network Theory (CCN), Technische Universität Dresden, Helmholtzstr. 18, 01069 Dresden, Germany.ORCID http://orcid.org/0000-0002-2180-7861
Peter BirkholzInstitute for Acoustics and Speech Communication (IAS), Technische Universität Dresden, Helmholtzstr. 18, 01069 Dresden, Germany.ORCID http://orcid.org/0000-0003-0167-8123
Hans KleemannDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany.ORCID http://orcid.org/0000-0002-9773-6676
Karl LeoDresden Integrated Center for Applied Physics and Photonic Materials (IAPP), Nöthnitzer Str. 61, 01187 Dresden, Germany.ORCID http://orcid.org/0000-0003-3313-1843

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early detection of malign patterns in patients' biological signals can save millions of lives. Despite the steady improvement of artificial intelligence-based techniques, the practical clinical application of these methods is mostly constrained to an offline evaluation of the patients' data. Previous studies have identified organic electrochemical devices as ideal candidates for biosignal monitoring. However, their use for pattern recognition in real time was never demonstrated. Here, we produce and characterize brain-inspired networks composed of organic electrochemical transistors and use them for time-series predictions and classification tasks using the reservoir computing approach. To show their potential use for biofluid monitoring and biosignal analysis, we classify four classes of arrhythmic heartbeats with an accuracy of 88%. The results of this study introduce a previously unexplored paradigm for biocompatible computational platforms and may enable development of ultralow-power consumption hardware-based artificial neural networks capable of interacting with body fluids and biological tissues.

Identifiers

PMID34407948
PMCPMC8373129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.