Evidence map›Paper›PMID 34407929›Full record

ArticleScience advances2021

Acoustic tweezer with complex boundary-free trapping and transport channel controlled by shadow waveguides.

Junfei Li, Chen Shen, Tony Jun Huang, Steven A Cummer

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Self-Oscillation in Active Wires with Asymmetric Willis-Type Viscosity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junfei LiDepartment of Electrical and Computer Engineering, Duke University, Durham, NC 27708, USA.ORCID http://orcid.org/0000-0002-5184-1737
Chen ShenDepartment of Electrical and Computer Engineering, Duke University, Durham, NC 27708, USA.ORCID http://orcid.org/0000-0003-3535-8494
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA.ORCID http://orcid.org/0000-0003-1205-3313
Steven A CummerDepartment of Electrical and Computer Engineering, Duke University, Durham, NC 27708, USA. cummer@ee.duke.edu.ORCID http://orcid.org/0000-0002-0002-0613

Funding

AFS/SERS Saliva-based SARS-CoV-2 Earliest Infection and Antibodies DetectionU18TR003778 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HUANG, TONY JUN, KIM, YONG · 2021 to 2022
$1.8M
Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUG3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AN, JI YEONG, GALL, KENNETH A · 2019 to 2020
$823k
NCATS NIH HHS U18 TR003778NCATS NIH HHS UG3 TR002978NIGMS NIH HHS R01 GM132603
6 · The paper itself

Abstract

Acoustic tweezers use ultrasound for contact-free, bio-compatible, and precise manipulation of particles from millimeter to submicrometer scale. In microfluidics, acoustic tweezers typically use an array of sources to create standing wave patterns that can trap and move objects in ways constrained by the limited complexity of the acoustic wave field. Here, we demonstrate spatially complex particle trapping and manipulation inside a boundary-free chamber using a single pair of sources and an engineered structure outside the chamber that we call a shadow waveguide. The shadow waveguide creates a tightly confined, spatially complex acoustic field inside the chamber without requiring any interior structure that would interfere with net flow or transport. Altering the input signals to the two sources creates trapped particle motion along an arbitrary path defined by the shadow waveguide. Particle trapping, particle manipulation and transport, and Thouless pumping are experimentally demonstrated.

Identifiers

PMID34407929
PMCPMC8373113

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.