Evidence map›Paper›PMID 34407902›Full record

ArticleCardiology in the young2022

Intriguing new faces of Covid-19: persisting clinical symptoms and cardiac effects in children.

Nurdan Erol, Abdullah Alpinar, Cigdem Erol, Erdal Sari, Kubra Alkan

Open access · bronzeAbstract read
In one paragraph

Article in Cardiology in the young, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 7 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 7 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  4. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  5. Pooled it
  6. Short and Long-Term Wellbeing of Children following SARS-CoV-2 Infection: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  8. Review
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  14. Article
  15. Systematic Review of the Prevalence of Long COVID.Open forum infectious diseases · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Children and long-COVID: Do they go together?Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  20. Post‑COVID‑19 syndrome in children (Review).Experimental and therapeutic medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nurdan ErolHealth Sciences University, Zeynep Kamil Gynecology and Pediatrics Training and Research Hospital, Pediatric Clinics, Uskudar, Istanbul 34668, Turkey.ORCID https://orcid.org/0000-0002-9650-2077
Abdullah AlpinarHealth Sciences University, Zeynep Kamil Gynecology and Pediatrics Training and Research Hospital, Pediatric Clinics, Uskudar, Istanbul 34668, Turkey.
Cigdem ErolIstanbul University Informatics Department, Beyazit, Fatih, Istanbul 34452, Turkey.
Erdal SariHealth Sciences University, Zeynep Kamil Gynecology and Pediatrics Training and Research Hospital, Pediatric Clinics, Uskudar, Istanbul 34668, Turkey.
Kubra AlkanHealth Sciences University, Zeynep Kamil Gynecology and Pediatrics Training and Research Hospital, Pediatric Clinics, Uskudar, Istanbul 34668, Turkey.
Zeynep Kamil Hospital · TRIstanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was conducted to evaluate the persisting Covid-19-related symptoms of the cases included in our study and to assess their cardiac findings to determine the impact of Covid-19 on children's cardiovascular health.

methodsIn this study, 121 children between the ages of 0- and 18 with Covid-19 were evaluated based on their history, blood pressure values, and electrocardiography and echocardiography results. These findings were compared with the findings of the control group which consisted of 95 healthy cases who were in the same age range as the study group and did not have Covid-19. The results were evaluated using the statistics program, SPSS 21.

resultsThere was no significant difference between the study group and the control group in terms of age, weight, and body mass index. The clinical symptoms (chest and back pain, dizziness, headache, palpitation, fatigue, shortness of breath, loss of balance, coughing) of 37.2% of the cases persisted for at least 1 month after Covid-19 recovery. Statistically significant differences were found in systolic blood pressure, left ventricular ejection fraction, relative wall thickness, and tricuspid annular plane systolic excursion.

conclusionThe continuation of some cases' clinical symptoms post-recovery indicates that long Covid infection can be observed in children. The fact that statistically significant differences were observed between the echocardiographic parameters of the study and control groups suggests that Covid-19 may have effects on the cardiovascular system. To shed light on the long Covid cases among children and the infection's cardiac impacts, it would be beneficial to conduct more comprehensive studies on this matter.

Indexed as

COVID-19AdolescentChildChild, PreschoolEchocardiographyHumansInfantInfant, NewbornPost-Acute COVID-19 SyndromeStroke VolumeVentricular Function, Leftcardiac involvementCovid-19echocardiographylong Covidmyocarditissystolic blood pressure

Identifiers

PMID34407902
PMCPMC8438511
OpenAlexW3194929936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.