ArticlePilot and feasibility studies2021
Planning and optimising a digital intervention to protect older adults' cognitive health.
Article in Pilot and feasibility studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Patient and Carer-Related Facilitators and Barriers to the Adoption of Assistive Technologies for the Care of Older Adults: Systematic Review.JMIR aging · 2025Pooled it
- Pooled it
- Article
- A digital intervention to protect cognitive health in older adults with cognitive impairment: a three-arm, open-label, randomised controlled trial.The Lancet. Primary care · 2026Article
- ENHANCE (Tailored Intervention for Brain Health and Cognitive Enrichment for Cognitive Health), a Coach-Supported Digital Intervention for Dementia Prevention in Underserved Older Adults: Co-Design and Usability Study.Journal of medical Internet research · 2026Article
- Article
- Development of a Cystic Fibrosis Weight Management Programme: protocol for a co-design study.NIHR open research · 2026Article
- Perceptions About Dyadic Physical Activity Intervention for Rural-Dwelling People With Cognitive Impairment.Journal of aging and physical activity · 2025Article
- Awareness, facilitators, barriers, and behaviours surrounding brain health: a large-scale cross-sectional survey of adults across UK and Ireland.BMC public health · 2025Article
- Implementing a Digital Physical Activity Intervention for Older Adults: Qualitative Study.JMIR aging · 2025Article
- Article
- Using the Person-Based Approach to Co-Create and Optimize an App-Based Intervention to Support Better Sleep for Adolescents in the United Kingdom: Mixed Methods Study.JMIR human factors · 2024Article
- Development of the intelligent knee osteoarthritis lifestyle app: a person-based approach.BMC musculoskeletal disorders · 2024Article
- Supporting patients to prepare for total knee replacement: Evidence-, theory- and person-based development of a 'Virtual Knee School' digital intervention.Health expectations : an international journal of public participation in health care and health policy · 2023Article
- Article
- The effects of a mobile-based multi-domain intervention on cognitive function among older adults.Preventive medicine reports · 2023Article
- Planning and designing a self-compassion intervention for family carers of people living with dementia: a person-based and co-design approach.BMC geriatrics · 2022Article
- Article
- Parallel randomized controlled feasibility trials of the "Active Brains" digital intervention to protect cognitive health in adults aged 60-85.Frontiers in public health · 2022Article
- The person-based approach to intervention development: A scoping review of methods and applications.Digital healthReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 9 institutions in 3 countries.
Funding
Abstract
backgroundBy 2050, worldwide dementia prevalence is expected to triple. Affordable, scalable interventions are required to support protective behaviours such as physical activity, cognitive training and healthy eating. This paper outlines the theory-, evidence- and person-based development of 'Active Brains': a multi-domain digital behaviour change intervention to reduce cognitive decline amongst older adults.
methodsDuring the initial planning phase, scoping reviews, consultation with PPI contributors and expert co-investigators and behavioural analysis collated and recorded evidence that was triangulated to inform provisional 'guiding principles' and an intervention logic model. The following optimisation phase involved qualitative think aloud and semi-structured interviews with 52 older adults with higher and lower cognitive performance scores. Data were analysed thematically and informed changes and additions to guiding principles, the behavioural analysis and the logic model which, in turn, informed changes to intervention content.
resultsScoping reviews and qualitative interviews suggested that the same intervention content may be suitable for individuals with higher and lower cognitive performance. Qualitative findings revealed that maintaining independence and enjoyment motivated engagement in intervention-targeted behaviours, whereas managing ill health was a potential barrier. Social support for engaging in such activities could provide motivation, but was not desirable for all. These findings informed development of intervention content and functionality that appeared highly acceptable amongst a sample of target users.
conclusionsA digitally delivered intervention with minimal support appears acceptable and potentially engaging to older adults with higher and lower levels of cognitive performance. As well as informing our own intervention development, insights obtained through this process may be useful for others working with, and developing interventions for, older adults and/or those with cognitive impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.