Evidence map›Paper›PMID 34407881›Full record

ArticleParasites & vectors2021

Evaluation of a mosquito home system for controlling Aedes aegypti.

Ahmad Mohiddin Mohd Ngesom, Anis Ahmad Razi, Nur Syahirah Azizan, Nazni Wasi Ahmad, Asmalia Md Lasim, Yanfeng Liang, David Greenhalgh, Jasmine Chia Siew Min, Mazrura Sahani, Rozita Hod and 1 more

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Ahmad Mohiddin Mohd NgesomCenter for Toxicology and Health Risk, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Anis Ahmad RaziCenter for Toxicology and Health Risk, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Nur Syahirah AzizanCenter for Toxicology and Health Risk, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Nazni Wasi AhmadMedical Entomology Unit, Infectious Disease Research Centre, Institute for Medical Research, National Institute of Health, Ministry of Health, 40170, Shah Alam, Selangor, Malaysia.
Asmalia Md LasimPhytochemistry Unit, Herbal Medicine Research Centre (HMRC), Institute for Medical Research, National Institute of Health, Ministry of Health, 40170, Shah Alam, Selangor, Malaysia.
Yanfeng LiangDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow, G1 1XH, UK.
David GreenhalghDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow, G1 1XH, UK.
Jasmine Chia Siew MinDepartment of Biomedical Science, Faculty of Medicine and Health Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Mazrura SahaniCenter for Toxicology and Health Risk, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Rozita HodDepartment of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, 50600, Cheras, Kuala Lumpur, Malaysia.
Hidayatulfathi OthmanCenter for Toxicology and Health Risk, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia. hida@ukm.edu.my.
National University of Malaysia · MYUniversity of Strathclyde · GBInstitute for Medical Research · MYMinistry of Health · MYUniversiti Putra Malaysia · MY

Funding

Dengue Tech Challenge 2016 Grant, under the Newton-Ungku Omar Fund Partnership AIM/ PlaTCOM/ HIP2/ CCGF/ 2016/ 088
6 · The paper itself

Abstract

backgroundDengue is a significant public health issue that is caused by Aedes spp. mosquitoes. The current vector control methods are unable to effectively reduce Aedes populations and thus fail to decrease dengue transmission. Hence, there is an urgent need for new tools and strategies to reduce dengue transmission in a wide range of settings. In this study, the Mosquito Home System (MHS) and Mosquito Home Aqua (MHAQ) formulations were assessed as commercial autodissemination traps in laboratory and small-scale field trials.

methodMultiple series of laboratory and small-scale field trials were performed to assess the efficacy of MHS and MHAQ exposed to Ae. aegypti. In the laboratory trials, various parameters such as fecundity, fertility, wing size, oviposition preferences, residual effects, and MHAQ transference to other containers through controlled experiments were tested. For small-scale field trials, the efficacy of the MHS and MHAQ approaches was determined to ascertain whether wild mosquitoes could transfer the MHAQ formulation from MHS stations to ovitraps.

resultsThe data revealed that Ae. aegypti was highly susceptible to low concentrations of MHAQ formulations and had a residual effect of up to 3 months, with MHAQ exposure affecting fecundity, fertility, and mosquito wing size. In the oviposition studies, gravid females strongly preferred the hay infusion compared to tap water and MHAQ during egg-laying in the laboratory. Nevertheless, the use of commercial MHAQ by MHS was highly attractive in field settings compared to conventional ovitraps among local Aedes spp. mosquitoes. In addition, MHAQ horizontal transfer activities in the laboratory and small-scale field trials were demonstrated through larval bioassays. These findings demonstrated the potential of MHAQ to be transferred to new containers in each study site.

conclusionThis study provided proof of principle for the autodissemination of MHAQ. Through further refinement, this technique and device could become an effective oviposition trap and offer an alternative preventive tool for vector control management.

Indexed as

AedesAnimalsFemaleInsecticidesLarvaMosquito ControlMosquito VectorsOvipositionInsecticidesAutodisseminationHorizontal transferInhibition emergencesInsect growth regulatorsVector control management

Identifiers

PMID34407881
PMCPMC8375193
OpenAlexW3194105920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.