Evidence map›Paper›PMID 34407793›Full record

ArticleBMC pregnancy and childbirth2021

Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome: a case report.

Amir Hossein Norooznezhad, Maryam Nurzadeh, Mohammad Hasan Darabi, Mahsa Naemi

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. HELLP Syndrome and COVID-19; association or accident: A case series.Journal of family medicine and primary care · 2022
    Article
  4. COVID-19: A Cause of HELLP Syndrome? A Case Report.International journal of women's health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Amir Hossein NorooznezhadMedical Biology Research Center, Health Institute Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Maryam NurzadehDepartment of Obstetrics and Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hasan DarabiMedical Biology Research Center, Health Institute Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mahsa NaemiMaternal, Fetal and Neonatal Research Center, Vali-Asr Hospital, Imam Khomeini Hospital Complexes, Tehran University of Medical Sciences, Tehran, Iran. mahsanaemi@yahoo.com.
Tehran University of Medical Sciences · IRKermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) still is a global emergency. According to the studies, pregnant women are of the at risk populations and any underlying disease(s) might even worsen their condition. The aim of this study is reporting a complex case of immune thrombocytopenic purpura (ITP) during pregnancy who has been diagnosed with COVID-19 as well as suspicion of HELLP syndrome. CASE PRESENTATION: A 24-year-old woman with a platelet count of 6000/mL and resistance to conventional therapies was referred. A day after starting 0.5 g/day of methylprednisolone for her, fever and a decrease in SpO2 presented. According to the paraclinical investigations, COVID-19 was diagnosed and the conventional COVID-19 treatments started for her (the methylprednisolone pulse stopped). Due to the increased liver enzymes and low platelet count, with suspicion of HELLP syndrome, cesarean section surgery was performed which resulted in a healthy neonate. Then, the methylprednisolone pulse was restarted for and she developed an increase in the platelet count.

conclusionIt is not clear how COVID-19 and pregnancy affected the patient's condition and the underlying disease; however, it seems the delivery and/or restarting the methylprednisolone pulses caused improvement in her condition.

Indexed as

Antiviral AgentsCesarean SectionCOVID-19COVID-19 Drug TreatmentDrug ResistanceFemaleHELLP SyndromeHumansInfant, NewbornMethylprednisolonePlatelet CountPregnancyPregnancy Complications, HematologicPregnancy Complications, InfectiousPulse Therapy, DrugPurpura, Thrombocytopenic, IdiopathicAntiviral AgentsMethylprednisoloneCOVID-19Immune thrombocytopenic purpuraImmunosuppressionPregnancy

Identifiers

PMID34407793
PMCPMC8371944
OpenAlexW3194984297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.