Evidence map›Paper›PMID 34407559›Full record

ArticleApplied clinical informatics2021

Evaluation of Electronic Health Record-Based Suicide Risk Prediction Models on Contemporary Data.

Rod L Walker, Susan M Shortreed, Rebecca A Ziebell, Eric Johnson, Jennifer M Boggs, Frances L Lynch, Yihe G Daida, Brian K Ahmedani, Rebecca Rossom, Karen J Coleman and 1 more

Abstract read
In one paragraph

Article in Applied clinical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Behavior of prediction performance metrics with rare events.Journal of clinical epidemiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rod L WalkerKaiser Permanente Washington Health Research Institute, Seattle, Washington, United States.
Susan M ShortreedKaiser Permanente Washington Health Research Institute, Seattle, Washington, United States.
Rebecca A ZiebellKaiser Permanente Washington Health Research Institute, Seattle, Washington, United States.
Eric JohnsonKaiser Permanente Washington Health Research Institute, Seattle, Washington, United States.
Jennifer M BoggsKaiser Permanente Colorado, Institute for Health Research, Aurora, Colorado, United States.
Frances L LynchKaiser Permanente Northwest, Center for Health Research, Portland, Oregon, United States.
Yihe G DaidaKaiser Permanente Hawaii, Center for Integrated Health Care Research, Honolulu, Hawaii, United States.
Brian K AhmedaniHenry Ford Health System, Center for Health Policy & Health Services Research, Detroit, Michigan, United States.
Rebecca RossomDepartment of Research, HealthPartners Institute, Minneapolis, Minnesota, United States.
Karen J ColemanDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, United States.
Gregory E SimonKaiser Permanente Washington Health Research Institute, Seattle, Washington, United States.

Funding

SSRI's and SuicidalityU19MH092201 · NIMH · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIMON, GREGORY E. · 2010 to 2018
$19.5M
Whose Depression Are We Measuring?: Considering the role of place on Black women’s depression outcomesU19MH121738 · NIMH · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIMON, GREGORY E. · 2019 to 2023
$10.6M
NIMH NIH HHS U19 MH092201NIMH NIH HHS U19 MH121738
6 · The paper itself

Abstract

backgroundSuicide risk prediction models have been developed by using information from patients' electronic health records (EHR), but the time elapsed between model development and health system implementation is often substantial. Temporal changes in health systems and EHR coding practices necessitate the evaluation of such models in more contemporary data.

objectivesA set of published suicide risk prediction models developed by using EHR data from 2009 to 2015 across seven health systems reported c-statistics of 0.85 for suicide attempt and 0.83 to 0.86 for suicide death. Our objective was to evaluate these models' performance with contemporary data (2014-2017) from these systems.

methodsWe evaluated performance using mental health visits (6,832,439 to mental health specialty providers and 3,987,078 to general medical providers) from 2014 to 2017 made by 1,799,765 patients aged 13+ across the health systems. No visits in our evaluation were used in the previous model development. Outcomes were suicide attempt (health system records) and suicide death (state death certificates) within 90 days following a visit. We assessed calibration and computed c-statistics with 95% confidence intervals (CI) and cut-point specific estimates of sensitivity, specificity, and positive/negative predictive value.

resultsModels were well calibrated; 46% of suicide attempts and 35% of suicide deaths in the mental health specialty sample were preceded by a visit (within 90 days) with a risk score in the top 5%. In the general medical sample, 53% of attempts and 35% of deaths were preceded by such a visit. Among these two samples, respectively, c-statistics were 0.862 (95% CI: 0.860-0.864) and 0.864 (95% CI: 0.860-0.869) for suicide attempt, and 0.806 (95% CI: 0.790-0.822) and 0.804 (95% CI: 0.782-0.829) for suicide death.

conclusionPerformance of the risk prediction models in this contemporary sample was similar to historical estimates for suicide attempt but modestly lower for suicide death. These published models can inform clinical practice and patient care today.

Indexed as

Electronic Health RecordsSuicide, AttemptedHumansPredictive Value of TestsRisk Factors

Identifiers

PMID34407559
PMCPMC8373461

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.