ArticleNeuroImage2021
Laminar dynamics of high amplitude beta bursts in human motor cortex.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Transient frontal spectral events from EEG predict antidepressant response to sertraline in depression.Journal of psychiatric research · 2026Trial
- Multilayer MEG source modelling enables depth-resolved laminar inference in humans.Nature communications · 2026Article
- Frequency and laminar profile of feature-specific visual activity revealed by interleaved EEG-fMRI.eLife · 2026Article
- The alpha rhythm: from physiology to behavior.Physiological reviews · 2026Review
- Brain-computer interface-based neurofeedback training enables transferable control of cortical state switching in humans.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Uncovering putative neural mechanisms of neurotherapeutic impacts on EEG using the Human Neocortical Neurosolver.bioRxiv : the preprint server for biology · 2026Article
- β-Bursting as a Sensitive Neural Marker of Inhibitory Control in Healthy Older Adults: A Linear Mixed-Effects Modeling and Threshold-Free Cluster Approach.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Cortical and basal ganglia beta oscillations and frequency-dependent DBS effects in the A53T Parkinson's disease rat model.NPJ Parkinson's disease · 2026Article
- Testing circuit-level theories of consciousness in humans.Trends in cognitive sciences · 2026Review
- Mapping Executive Function Performance Based on Resting-State EEG in Healthy Individuals: A Systematic and Mechanistic Review.Journal of clinical medicine · 2026Review
- Transient frontal spectral events from EEG predict antidepressant response to sertraline in depression.medRxiv : the preprint server for health sciences · 2026Article
- Functional heterogeneity of beta bursts in childhood reveals a dimensional neural signature of motor skill.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Article
- Projection of Cortical Beta Band Oscillations to a Motor Neuron Pool across the Full Range of Recruitment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- High-power transient 12-30 Hz beta event features as early biomarkers of Alzheimer's disease conversion: An MEG study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Inferring laminar origins of MEG signals with optically pumped magnetometers (OPMs): A simulation study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Transcallosal generation of phase-aligned beta bursts underlies TMS-induced interhemispheric inhibition.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Site-specific seeding of Lewy pathology induces distinct pre-motor cellular and dendritic vulnerabilities in the cortex.Nature communications · 2024Article
- Cortico-striatal beta oscillations as a reward-related signal.Cognitive, affective & behavioral neuroscience · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Motor cortical activity in the beta frequency range is one of the strongest and most studied movement-related neural signals. At the single trial level, beta band activity is often characterized by transient, high amplitude, bursting events rather than slowly modulating oscillations. The timing of these bursting events is tightly linked to behavior, suggesting a more dynamic functional role for beta activity than previously believed. However, the neural mechanisms underlying beta bursts in sensorimotor circuits are poorly understood. To address this, we here leverage and extend recent developments in high precision MEG for temporally resolved laminar analysis of burst activity, combined with a neocortical circuit model that simulates the biophysical generators of the electrical currents which drive beta bursts. This approach pinpoints the generation of beta bursts in human motor cortex to distinct excitatory synaptic inputs to deep and superficial cortical layers, which drive current flow in opposite directions. These laminar dynamics of beta bursts in motor cortex align with prior invasive animal recordings within the somatosensory cortex, and suggest a conserved mechanism for somatosensory and motor cortical beta bursts. More generally, we demonstrate the ability for uncovering the laminar dynamics of event-related neural signals in human non-invasive recordings. This provides important constraints to theories about the functional role of burst activity for movement control in health and disease, and crucial links between macro-scale phenomena measured in humans and micro-circuit activity recorded from animal models.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.