Evidence map›Paper›PMID 34407423›Full record

ReviewThe American journal of medicine2021

Transcranial Magnetic Stimulation Treatment for Smoking Cessation: An Introduction for Primary Care Clinicians.

Jonathan R Young, Jeffrey T Galla, Lawrence G Appelbaum

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in The American journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06765824 (Transcranial Magnetic Stimulation in the Treatment of Dual Disorders), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06765824 phase3not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Transcranial Magnetic Stimulation in the Treatment of Dual Disorders: Study in Patients with Depression and Tobacco Addiction

TypeinterventionalSponsorCardenal Herrera UniversityRan2025 to 2026Enrolled36ConditionsMajor Depression, Tobacco AddictionArmsRepetitive Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
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  8. Nicotine dependence and insula subregions: functional connectivity and cue-induced activation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jonathan R YoungDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC; Duke Clinical Research Institute (DCRI), Duke University School of Medicine, Durham, NC; Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC), Durham Veterans Affairs Health Care System, NC; Durham Veterans Affairs Health Care System, NC. Electronic address: jonathan.young@duke.edu.
Jeffrey T GallaDepartment of Psychology and Neuroscience, Trinity College of Arts and Sciences, Duke University, Durham, NC.
Lawrence G AppelbaumDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC; Center for Cognitive Neuroscience, Duke University, Durham, NC.
Duke University · US

Funding

Using fMRI-guided TMS to increase central executive function in older adults - Administrative SupplementU01AG050618 · NIA · DUKE UNIVERSITY · PI APPELBAUM, LAWRENCE G., CABEZA, ROBERTO · 2016 to 2019
$2.3M
Neuroimaging correlates and feasibility of transcranial magnetic stimulation (TMS) to improve smoking cessation outcomes in veterans with comorbid PTSDIK1CX002187 · VA · DURHAM VA MEDICAL CENTER · PI YOUNG, JONATHAN R · 2021 to 2023
–
CSRD VA IK1 CX002187NIA NIH HHS U01 AG050618
6 · The paper itself

Abstract

Tobacco use remains the number one preventable cause of death in the United States, resulting in significant public health and economic costs. Despite progress in reducing tobacco use through pharmacotherapy and psychotherapy smoking cessation interventions, additional treatment options are still needed to improve treatment effectiveness. As an adjunctive treatment, the US Food and Drug Administration recently cleared transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique, as an aid for smoking cessation in adults. Given that most smoking cessation interventions occur in the primary care setting, this article aims to introduce TMS, to provide an overview of the evidence of TMS for smoking cessation, and to outline the procedures for implementing TMS in the primary care setting when referral to an interventional psychiatrist is not possible. With growing scientific evidence and increasing regulatory approval of TMS for smoking cessation, this novel treatment option is now available for patients who want to quit smoking but have been unsuccessful with pharmacologic approaches.

Indexed as

Primary Health CareHumansPsychotherapySmoking CessationSmoking Cessation AgentsTobacco Use DisorderTranscranial Magnetic StimulationSmoking Cessation AgentsAddictionSmoking cessationTMSTobaccoTranscranial magnetic stimulation

Identifiers

PMID34407423
PMCPMC8607981
OpenAlexW3195392544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.