Evidence map›Paper›PMID 34407132›Full record

ArticlePloS one2021

Cost-effectiveness of uterine balloon tamponade devices in managing atonic post-partum hemorrhage at public health facilities in India.

Beena Nitin Joshi, Siddesh Sitaram Shetty, Kusum Venkobrao Moray, Oshima Sachin, Himanshu Chaurasia

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Beena Nitin JoshiDepartment of Operational Research, Indian Council of Medical Research - National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.ORCID 0000-0003-2187-4922
Siddesh Sitaram ShettyRegional Resource Hub for Health Technology Assessment, Indian Council of Medical Research - National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.ORCID 0000-0003-0696-1622
Kusum Venkobrao MorayRegional Resource Hub for Health Technology Assessment, Indian Council of Medical Research - National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Oshima SachinDepartment of Health Research, Ministry of Health and Family Welfare, New Delhi, India.
Himanshu ChaurasiaRegional Resource Hub for Health Technology Assessment, Indian Council of Medical Research - National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
National Institute for Research in Reproductive Health · INMinistry of Health and Family Welfare · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePost-partum hemorrhage (PPH) is the leading direct cause of maternal mortality in India. Uterine balloon tamponade (UBT) is recommended for atonic PPH cases not responding to uterotonics. This study assessed cost-effectiveness of three UBT devices used in Indian public health settings.

methodsA decision tree model was built to assess cost-effectiveness of Bakri-UBT and low-cost ESM-UBT alternatives as compared to the recommended standard of care i.e. condom-UBT intervention. A hypothetical annual cohort of women eligible for UBT intervention after experiencing atonic PPH in Indian public health facilities were evaluated for associated costs and outcomes over life-time horizon using a disaggregated societal perspective. Costs by undertaking primary costing and clinical parameters from published literature were used. Incremental cost per Disability Adjusted Life Years (DALY) averted, number of surgeries and maternal deaths with the interventions were estimated. An India specific willingness to pay threshold of INR 24,211 (USD 375) was used to evaluate cost-effectiveness. Detailed sensitivity analysis and expected value of information analysis was undertaken.

resultsESM-UBT at base-case Incremental Cost-Effectiveness Ratio (ICER) of INR -2,412 (USD 37) per DALY averted is a cost-saving intervention i.e. is less expensive and more effective as compared to condom-UBT. Probabilistic sensitivity analysis however shows an error probability of 0.36, indicating a degree of uncertainty around model results. Bakri-UBT at an ICER value of INR -126,219 (USD -1,957) per DALY averted incurs higher incremental societal costs and is less effective as compared to condom-UBT. Hence, Bakri-UBT is not cost-effective.

conclusionFor atonic PPH management in India, condom-UBT offers better value as compared to Bakri-UBT. Given the limited clinical effectiveness evidence and uncertainty in sensitivity analysis, cost-saving result for ESM-UBT must be considered with caution. Future research may focus on generating high quality comparative clinical evidence for UBT devices to facilitate policy decision making.

Indexed as

Cost-Benefit AnalysisAdultDecision TreesDisability-Adjusted Life YearsFemaleHealth FacilitiesHumansIndiaMaternal MortalityParturitionPostpartum HemorrhagePregnancyUterine Balloon Tamponade

Identifiers

PMID34407132
PMCPMC8372914
OpenAlexW3195188297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.